1,8-Цинеолна синтаза
| 1,8-Cineolna sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.3.108 | ||||||||
| CAS broj | 110637-19-9 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
1,8-Cineolna sintaza (EC 4.2.3.108, 1,8-cineolna ciklaza, geranilna pirofoshat:1,8-cineolna ciklaza, 1,8-cineolna sintetaza) je enzim sa sistematskim imenom geranil-difosfat difosfat-lijaza (ciklizacija, formira 1,8-cineol).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- geranil difosfat + H2O 1,8-cineol + difosfat
Za dejstvo ovog enzima je neophodan jon Mn2+ ili Zn2+.
Reference[уреди | уреди извор]
- ^ Croteau, R., Alonso, W.R., Koepp, A.E. and Johnson, M.A. (1994). „Biosynthesis of monoterpenes: partial purification, characterization, and mechanism of action of 1,8-cineole synthase”. Arch. Biochem. Biophys. 309: 184—192. PMID 8117108.
- ^ Wise, M.L., Savage, T.J., Katahira, E. and Croteau, R. (1998). „Monoterpene synthases from common sage (Salvia officinalis). cDNA isolation, characterization, and functional expression of (+)-sabinene synthase, 1,8-cineole synthase, and (+)-bornyl diphosphate synthase”. J. Biol. Chem. 273: 14891—14899. PMID 9614092.
- ^ Peters, R.J. & Croteau, R.B. (2003). „Alternative termination chemistries utilized by monoterpene cyclases: chimeric analysis of bornyl diphosphate, 1,8-cineole, and sabinene synthases”. Arch. Biochem. Biophys. 417: 203—211. PMID 12941302.
- ^ Chen, F., Ro, D.K., Petri, J., Gershenzon, J., Bohlmann, J., Pichersky, E. and Tholl, D. (2004). „Characterization of a root-specific Arabidopsis terpene synthase responsible for the formation of the volatile monoterpene 1,8-cineole”. Plant Physiol. 135: 1956—1966. PMID 15299125.
- ^ Keszei, A., Brubaker, C.L., Carter, R., Kollner, T., Degenhardt, J. and Foley, W.J. (2010). „Functional and evolutionary relationships between terpene synthases from Australian Myrtaceae”. Phytochemistry. 71: 844—852. PMID 20399476.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- 1,8-cineole+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
