2-C-метил-D-еритритол 4-фосфат цитидилилтрансфераза
| 2-C-metil-D-eritritol 4-fosfat citidililtransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.7.7.60 | ||||||||
| CAS broj | 251990-59-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
2-C-metil-D-eritritol 4-fosfat citidililtransferaza (EC 2.7.7.60, MEP citidililtransferaza) je enzim sa sistematskim imenom CTP:2-C-metil-D-eritritol 4-fosfat citidililtransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- CTP + 2-C-metil-D-eritritol 4-fosfat difosfat + 4-(citidin 5'-difosfo)-2-C-metil-D-eritritol
Za rad enzim iz Escherichia coli je neophodan jon Mg2+ ili Mn2+.
Reference[уреди | уреди извор]
- ^ Rohdich, F., Wungsintaweekul, J., Fellermeier, M., Sagner, S., Herz, S., Kis, K., Eisenreich, W., Bacher, A. and Zenk, M.H. (1999). „Cytidine 5′-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erithritol”. Proc. Natl Acad. Sci. USA. 96: 11758—11763. PMID 10518523.
- ^ Kuzuyama, T., Takagi, M., Kaneda, K., Dairi, T. and Seto, H. (2000). „Formation of 4-(cytidine 5′-diphospho)-2-C-methyl-D-erythritol from 2-C-methyl-D-erythritol 4-phosphate by 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, a new enzyme in the nonmevalonate pathway”. Tetrahedron Lett. 41: 703—706.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- 2-C-methyl-D-erythritol+4-phosphate+cytidylyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
