Арабинофуранан 3-О-арабинозилтрансфераза
| Arabinofuranan 3-O-arabinoziltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.2.47 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Arabinofuranan 3-O-arabinoziltransferaza (EC 2.4.2.47, AftC) je enzim sa sistematskim imenom alfa-(1->5)-arabinofuranan:trans,oktacis-dekaprenilfosfo-beta-D-arabinofuranoza 3-O-alfa-D-arabinofuranoziltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Dodaje alfa-D-arabinofuranozilnu grupu sa trans,oktacis-dekaprenilfosfo-beta-D-arabinofuranoze u 3-O-poziciju alfa-(1->5)-arabinofurananskog lanca vezanog za beta-(1->5)-galaktofurananski lanac
Ovaj enzim je izolovan iz [[Mycobakterija smegmatis]]. On učestvuje u formiranju ćelijskog zida mikobakterija.
Reference[уреди | уреди извор]
- ^ Birch, H.L., Alderwick, L.J., Bhatt, A., Rittmann, D., Krumbach, K., Singh, A., Bai, Y., Lowary, T.L., Eggeling, L. and Besra, G.S. (2008). „Biosynthesis of mycobacterial arabinogalactan: identification of a novel α(1-→3) arabinofuranosyltransferase”. Mol. Microbiol. 69: 1191—1206. PMID 18627460.
- ^ Zhang, J., Angala, S.K., Pramanik, P.K., Li, K., Crick, D.C., Liav, A., Jozwiak, A., Swiezewska, E., Jackson, M. and Chatterjee, D. (2011). „Reconstitution of functional mycobacterial arabinosyltransferase AftC proteoliposome and assessment of decaprenylphosphorylarabinose analogues as arabinofuranosyl donors”. ACS Chem. Biol. 6: 819—828. PMID 21595486.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Arabinofuranan+3-O-arabinosyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
