Panteteinska hidrolaza
| Panteteinska hidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.1.92 | ||||||||
| CAS broj | 56093-18-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Panteteinska hidrolaza (EC 3.5.1.92, panteteinaza, vanin, vanin-1) je enzim sa sistematskim imenom (R)-pantetein amidohidrolaza.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (R)-pantetein + H2O (R)-pantotenat + 2-aminoetantiol
Ovaj enzim hidrolizuje jednu od amidnih veza panteteina.
Reference[uredi | uredi izvor]
- ^ Duprè, S. and Cavallini, D. (1979). „Purification and properties of pantetheinase from horse kidney”. Methods Enzymol. 62: 262—267. PMID 440106.
- ^ Duprè, S., Chiaraluce, R., Nardini, M., Cannella, C., Ricci, G. and Cavallini, D. (1984). „Continuous spectrophotometric assay of pantetheinase activity”. Anal. Biochem. 142: 175—181. PMID 6549111.
- ^ Maras, B., Barra, D., Duprè, S. and Pitari, G. (1999). „Is pantetheinase the actual identity of mouse and human vanin-1 proteins?”. FEBS Lett. 461: 149—152. PMID 10567687.
- ^ Aurrand-Lions, M., Galland, F., Bazin, H., Zakharyev, V.M., Imhof, B.A. and Naquet, P. (1996). „Vanin-1, a novel GPI-linked perivascular molecule involved in thymus homing”. Immunity. 5: 391—405. PMID 8934567.
- ^ Pitari, G., Malergue, F., Martin, F., Philippe, J.M., Massucci, M.T., Chabret, C., Maras, B., Duprè, S., Naquet, P. and Galland, F. (2000). „Pantetheinase activity of membrane-bound Vanin-1: lack of free cysteamine in tissues of Vanin-1 deficient mice”. FEBS Lett. 483: 149—154. PMID 11042271.
- ^ Martin, F., Malergue, F., Pitari, G., Philippe, J.M., Philips, S., Chabret, C., Granjeaud, S., Mattei, M.G., Mungall, A.J., Naquet, P. and Galland, F. (2001). „Vanin genes are clustered (human 6q22-24 and mouse 10A2B1) and encode isoforms of pantetheinase ectoenzymes”. Immunogenetics. 53: 296—306. PMID 11491533.
- ^ Pace, H.C. & Brenner, C. (2001). „The nitrilase superfamily: classification, structure and function”. Genome Biol. 2: 0001.—001.9. PMID 11380987.
Literatura[uredi | uredi izvor]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[uredi | uredi izvor]
- Pantetheine+hydrolase na US National Library of Medicine Medical Subject Headings (MeSH)
