Saharoza-fosfat sintaza
| Saharoza-fosfat sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.14 | ||||||||
| CAS broj | 2604333 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Saharoza-fosfat sintaza (EC 2.4.1.14, UDP-glukoza fruktoza-fosfat glukoziltransferaza, saharozafosfat UDP glukoziltransferaza, UDP-glukoza-fruktoza-fosfat glukoziltransferaza, SPS, uridin difosfoglukoza-fruktoza fosfat glukoziltransferaza, saharoza 6-fosfat sintaza, saharoza fosfat sintetaza, saharoza fosfat-uridin difosfat glukoziltransferaza, saharoza fosfat sintaza) je enzim sa sistematskim imenom UDP-glukoza:D-fruktoza-6-fosfat 2-alfa-D-glukoziltransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-glukoza + D-fruktoza 6-fosfat UDP + saharoza 6F-fosfat
Za maksimalno dejstvo ovog enzima je neophodan Mg2+ ili Mn2+.
Reference[uredi | uredi izvor]
- ^ Mendicino, J. (1960). „Sucrose phosphate synthesis in wheat germ and green leaves”. J. Biol. Chem. 235: 3347—3352. PMID 13769376.
- ^ Curatti, L., Folco, E., Desplats, P., Abratti, G., Limones, V., Herrera-Estrella, L. and Salerno, G. (1998). „Sucrose-phosphate synthase from Synechocystis sp. strain PCC 6803: identification of the spsA gene and characterization of the enzyme expressed in Escherichia coli”. J. Bacteriol. 180: 6776—6779. PMID 9852031.
- ^ Huber, S.C. & Huber, J.L. (1996). „Role and regulation of sucrose-phosphate synthase in higher plants”. Annu. Rev. Plant Physiol. Plant Mol. Biol. 47: 431—444. PMID 15012296.
- ^ Cumino, A., Curatti, L., Giarrocco, L. and Salerno, G.L. (2002). „Sucrose metabolism: Anabaena sucrose-phosphate synthase and sucrose-phosphate phosphatase define minimal functional domains shuffled during evolution”. FEBS Lett. 517: 19—23. PMID 12062401.
- ^ Chua, T.K., Bujnicki, J.M., Tan, T.C., Huynh, F., Patel, B.K. and Sivaraman, J. (2008). „The structure of sucrose phosphate synthase from Halothermothrix orenii reveals its mechanism of action and binding mode”. Plant Cell. 20: 1059—1072. PMID 18424616.
Literatura[uredi | uredi izvor]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[uredi | uredi izvor]
- Sucrose-phosphate+synthase na US National Library of Medicine Medical Subject Headings (MeSH)
