Zingipain
| Zingipain | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.22.67 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Zingipain (EC 3.4.22.67, đimburna proteaza, GP-I, GP-II, đimburna proteaza II (Zingiber officinale), zingibain) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Preferentno razlaganje peptida sa prolinskim ostatko u P2 poziciji
Ovaj enzim je prisutanu đimburu (Zingiber officinale) i član je papainske familije.
Reference[uredi | uredi izvor]
- ^ Choi, K.H. & Laursen, R.A. (2000). „Amino-acid sequence and glycan structures of cysteine proteases with proline specificity from ginger rhizome Zingiber officinale”. Eur. J. Biochem. 267: 1516—1526. PMID 10691991.
- ^ Ohtsuki, K., Taguchi, K., Sato, K. and Kawabata, M. (1995). „Purification of ginger proteases by DEAE-Sepharose and isoelectric focusing”. Biochim. Biophys. Acta. 1243: 181—184. PMID 7873561.
- ^ Choi, K.H., Laursen, R.A. and Allen, K.N. (1999). „The 2.1 Å structure of a cysteine protease with proline specificity from ginger rhizome, Zingiber officinale”. Biochemistry. 38: 11624—11633. PMID 10512617.
Literatura[uredi | uredi izvor]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
