Acil-homoserin-laktonska acilaza
| Acil-homoserin-laktonska acilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.1.97 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Acil-homoserin-laktonska acilaza (EC 3.5.1.97, acil-homoserin laktonska acilaza, AHL-acilaza, AiiD, N-acil-homoserin laktonska acilaza, PA2385 protein, PvdQ, QuiP) je enzim sa sistematskim imenom N-acil-L-homoserin-lakton amidohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- N-acil-L-homoserin lakton + H2O L-homoserin lakton + karboksilat
Acil-homoserinske laktone (AHL) formiraju brojne bakterijske vrste.
Reference[уреди | уреди извор]
- ^ Sio, C.F., Otten, L.G., Cool, R.H., Diggle, S.P., Braun, P.G., Bos, R., Daykin, M., Cámara, M., Williams, P. and Quax, W.J. (2006). „Quorum quenching by an N-acyl-homoserine lactone acylase from Pseudomonas aeruginosa PAO1”. Infect. Immun. 74: 1673—1682. PMID 16495538.
- ^ Lin, Y.H., Xu, J.L., Hu, J., Wang, L.H., Ong, S.L., Leadbetter, J.R. and Zhang, L.H. (2003). „Acyl-homoserine lactone acylase from Ralstonia strain XJ12B represents a novel and potent class of quorum-quenching enzymes”. Mol. Microbiol. 47: 849—860. PMID 12535081.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Acyl-homoserine-lactone+acylase на US National Library of Medicine Medical Subject Headings (MeSH)
