Barbituraza
| Barbituraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.2.1 | ||||||||
| CAS broj | 9025-16-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Barbituraza (EC 3.5.2.1) je enzim sa sistematskim imenom barbiturat amidohidrolaza (formira 3-okso-3-ureidopropanoat).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- barbiturat + H2O 3-okso-3-ureidopropanoat
Ovaj enziom sadrži cink.
Reference[уреди | уреди извор]
- ^ Hayaishi, O. & Kornberg, A. (1952). „Metabolism of cytosine, thymine, uracil, and barbituric acid by bacterial enzymes”. J. Biol. Chem. 197: 717—723. PMID 12981104.
- ^ Soong, C.L., Ogawa, J. and Shimizu, S. (2001). „Novel amidohydrolytic reactions in oxidative pyrimidine metabolism: analysis of the barbiturase reaction and discovery of a novel enzyme, ureidomalonase”. Biochem. Biophys. Res. Commun. 286: 222—226. PMID 11485332.
- ^ Soong, C.L., Ogawa, J., Sakuradani, E. and Shimizu, S. (2002). „Barbiturase, a novel zinc-containing amidohydrolase involved in oxidative pyrimidine metabolism”. J. Biol. Chem. 277: 7051—7058. PMID 11748240.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Barbiturase на US National Library of Medicine Medical Subject Headings (MeSH)
