Beta-ketoacil-(acil-nosilac-protein) sintaza II

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Beta-ketoacil-(acil-nosilac-protein) sintaza II
Identifikatori
EC broj 2.3.1.179
CAS broj 1048648-42-5
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Beta-ketoacil-(acil-nosilac-protein) sintaza II (EC 2.3.1.179, KASII, KAS II, FabF, 3-oksoacil-acil nosilac protein sintaza I, beta-ketoacil-ACP sintaza II, (Z)-heksadec-11-enoil-(acil-nosilac-protein):malonil-(acil-nosilac-protein) C-aciltransferaza (dekarboksilacija)) je enzim sa sistematskim imenom (Z)-heksadek-11-enoil-(acil-nosilac protein):malonil-(acil-nosilac protein) C-aciltransferaza (dekarboksilacija).[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju

(Z)-heksadek-11-enoil-[acil-nosilac protein] + malonil-[acil-nosilac protein] \rightleftharpoons (Z)-3-oksooktadek-13-enoil-[acil-nosilac protein] + CO2 + [acil-nosilac protein]

Ovaj enzim učestvuje u sistemu biosinteze disociranih masnih kiselina kod biljki i bakterija.

Reference[уреди]

  1. ^ D'Agnolo, G., Rosenfeld, I.S. and Vagelos, P.R. (1975). „Multiple forms of β-ketoacyl-acyl carrier protein synthetase in Escherichia coli“. J. Biol. Chem. 250: 5289-5294. PMID 237914. 
  2. ^ Garwin, J.L., Klages, A.L. and Cronan, J.E., Jr.. (1980). „Structural, enzymatic, and genetic studies of β-ketoacyl-acyl carrier protein synthases I and II of Escherichia coli“. J. Biol. Chem. 255: 11949-11956. PMID 7002930. 
  3. ^ Price, A.C., Rock, C.O. and White, S.W. (2003). „The 1.3-Angstrom-resolution crystal structure of β-ketoacyl-acyl carrier protein synthase II from Streptococcus pneumoniae“. J. Bacteriol. 185: 4136-4143. PMID 12837788. 
  4. ^ Garwin, J.L., Klages, A.L. and Cronan, J.E., Jr. (1980). „β-Ketoacyl-acyl carrier protein synthase II of Escherichia coli. Evidence for function in the thermal regulation of fatty acid synthesis“. J. Biol. Chem. 255: 3263-3265. PMID 6988423. 
  5. ^ Magnuson, K., Carey, M.R. and Cronan, J.E., Jr. (1995). „The putative fabJ gene of Escherichia coli fatty acid synthesis is the fabF gene“. J. Bacteriol. 177: 3593-3595. PMID 7768872. 
  6. ^ Cronan, J.E., Jr. and Rock, C.O. (1996). „Biosynthesis of membrane lipids“. In Neidhardt, F.C.. Escherichia coli and Salmonella: Cellular and Molecular Biology. 1 (2nd ed.). Washington, DC: ASM Press. стр. 612-636. 

Литература[уреди]

  • Cronan, J.E., Jr. and Rock, C.O. (1996). „Biosynthesis of membrane lipids“. In Neidhardt, F.C.. Escherichia coli and Salmonella: Cellular and Molecular Biology. 1 (2nd ed.). Washington, DC: ASM Press. стр. 612-636. 

Spoljašnje veze[уреди]