Cistationinska b-sintaza
| Cistationinska b-sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 4.2.1.22 | ||||||||
| CAS broj | 9023-99-8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Cistationinska b-sintaza (EC 4.2.1.22, serinska sulfhidraza, beta-tionaza, metilcisteinska sintaza, cisteinska sintaza, serin sulfhidrilaza, L-serinska hidrolijaza (dodaje homocistein)) je enzim sa sistematskim imenom L-serin hidrolijaza (dodaje homocistein; formira L-cistationin).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-serin + L-homocistein L-cistationin + H2O
Ovaj enzim je piridoksal-fosfatni protein.
Reference[уреди | уреди извор]
- ^ Braunstein, A.E., Goryachinkova, E.V., Tolosa, E.A., Willhardt, I.H. and Yefremova, L.L. (1971). „Specificity and some other properties of liver serine sulphhydrase: evidence for its identity with cystathionine-synthase”. Biochim. Biophys. Acta,. 242: 247—260. PMID 5121611.
- ^ Nakagawa, H. & Kimura, H. (1968). „Purification and properties of cystathionine synthetase synthetase from rat liver: separation of cystathionine synthetase from serine dehydratase”. Biochem. Biophys. Res. Commun. 32: 209—214. PMID 5672136.
- ^ Schlossmann, K., Brüggemann, J. and Lynen, F. (1962). „Biosynthese des Cysteins. I. Nachweis und Isolierung der Serinsulfhydrase aus Bäckerhefe”. Biochem. Z. 336: 258—273. PMID 13991884.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Cystathionine+beta-synthase на US National Library of Medicine Medical Subject Headings (MeSH)
