(Acil-nosilac-protein) S-acetiltransferaza
(преусмерено са EC 2.3.1.38)
| (Acil-nosilac-protein) S-acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.38 | ||||||||
| CAS broj | 37257-16-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
(Acil-nosilac-protein) S-acetiltransferaza (EC 2.3.1.38, acetil koenzim A-acil-nosilac-protein transacilaza, (acil-nosilac-protein)acetiltransferaza, (ACP)acetiltransferaza, ACAT, acetil-KoA:(acil-nosilac-protein) S-acetiltransferaza) je enzim sa sistematskim imenom acetil-KoA:(acil-nosilac protein) S-acetiltransferaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acetil-KoA + [acil-nosilac protein] KoA + acetil-[acil-nosilac protein]
Ovaj enzim, zajedno sa EC 2.3.1.39, [acil-nosilac-protein] S-maloniltransferazom, je esencijalan za inicijaciju biosinteze masnih kiselina u bakterijama.
Reference[уреди | уреди извор]
- ^ Prescott, D.J. & Vagelos, P.R. (1972). „Acyl carrier protein”. Adv. Enzymol. Relat. Areas Mol. Biol. 36: 269—311. PMID 4561013.
- ^ Vance, D.E., Mituhashi, O. and Bloch, K. (1973). „Purification and properties of the fatty acid synthetase from Mycobacterium phlei”. J. Biol. Chem. 248: 2303—2309. PMID 4698221.
- ^ Williamson, I.P. & Wakil, S.J. (1966). „Studies on the mechanism of fatty acid synthesis. XVII. Preparation and general properties of acetyl coenzyme A and malonyl coenzyme A-acyl carrier protein transacylases”. J. Biol. Chem. 241: 2326—2332. PMID 5330116.
- ^ Lowe, P.N. & Rhodes, S. (1988). „Purification and characterization of [acyl-carrier-protein] acetyltransferase from Escherichia coli”. Biochem. J. 250: 789—796. PMID 3291856.
- ^ Tsay, J.T., Oh, W., Larson, T.J., Jackowski, S. and Rock, C.O. (1992). „Isolation and characterization of the β-ketoacyl-acyl carrier protein synthase III gene (fabH) from Escherichia coli K-12”. J. Biol. Chem. 267: 6807—6814. PMID 1551888.
- ^ Rangan, V.S. & Smith, S. (1997). „Alteration of the substrate specificity of the malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase domain of the multifunctional fatty acid synthase by mutation of a single arginine residue”. J. Biol. Chem. 272: 11975—11978. PMID 9115261.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- (acyl-carrier-protein)+S-acetyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
