Cijanatna hidrataza
(преусмерено са EC 4.2.1.104)
| Cijanatna hidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Cijanatna hidrataza homodekamer, E.Coli | |||||||||
| Identifikatori | |||||||||
| EC broj | 4.2.1.104 | ||||||||
| CAS broj | 37289-24-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Cijanatna hidrataza (EC 4.2.1.104, cijanatna lijaza, cijanatna hidrolaza, cijanatna aminohidrolaza, cijanatna C-N-lijaza) je enzim sa sistematskim imenom karbamat hidrolijaza.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju
- cijanat + HCO3- + 2 H+ NH3 + 2 CO2 (sveukupna reakcija)
- (1a) cijanat + HCO3- + H+ karbamat + CO2
- (1b) karbamat + H+ NH3 + CO2 (spontana reakcija)
Ovaj enzim, koji je pristuan u bakterijama i biljkama, posreduje razlaganje cijanata.
Reference[уреди | уреди извор]
- ^ Anderson, P.M. (1980). „Purification and properties of the inducible enzyme cyanase”. Biochemistry. 19: 2882—2888. PMID 6994799.
- ^ Johnson, W.V. & Anderson, P.M. (1987). „Bicarbonate is a recycling substrate for cyanase”. J. Biol. Chem. 262: 9021—9025. PMID 3110153.
- ^ Taussig, A. (1960). „T'he synthesis of the induced enzyme, "cyanase", in E. coli”. Biochim. Biophys. Acta. 44: 510—519. PMID 13775509.
- ^ Taussig, A. (1965). „Some properties of the induced enzyme cyanase”. Can. J. Biochem. 43: 1063—1069. PMID 5322950.
- ^ Anderson, P.M., Korte, J.J. and Holcomb, T.A. (1994). „Reaction of the N-terminal methionine residues in cyanase with diethylpyrocarbonate”. Biochemistry. 33: 14121—14125. PMID 7947823.
- ^ Kozliak, E.I., Fuchs, J.A., Guilloton, M.B. and Anderson, P.M. (1995). „Role of bicarbonate/CO2 in the inhibition of Escherichia coli growth by cyanate”. J. Bacteriol. 177: 3213—3219. PMID 7768821.
- ^ Walsh, M.A., Otwinowski, Z., Perrakis, A., Anderson, P.M. and Joachimiak, A. (2000). „Structure of cyanase reveals that a novel dimeric and decameric arrangement of subunits is required for formation of the enzyme active site”. Structure. 8: 505—514. PMID 10801492.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
