GRIP1 (gen)

Из Википедије, слободне енциклопедије
GRIP1

PDB prikaz baziran na 1m5z.
Dostupne strukture
2JIL
Identifikatori
Simboli GRIP1; GRIP
Vanjski ID OMIM604597 MGI1921303 HomoloGene12938 GeneCards: GRIP1 Gene
Pregled RNK izražavanja
PBB GE GRIP1 214018 at tn.png
podaci
Ortolozi
Vrsta Čovek Miš
Entrez 23426 74053
Ensembl ENSG00000155974 ENSMUSG00000034813
UniProt Q9Y3R0 Q925T6
RefSeq (mRNA) NM_001178074.1 NM_028736.1
RefSeq (protein) NP_001171545.1 NP_083012.1
Lokacija (UCSC) Chr 12:
66.74 - 67.2 Mb
Chr 10:
118.89 - 119.52 Mb
PubMed pretraga [1] [2]

GRIP1Gl (gutamatni receptor - interagujući protein 1) je protein koji je kod ljudi kodiran GRIP1 genom.[1][2]

Interakcije[уреди]

GRIP1 (gen) formira interakcije sa GRIA4,[3] metabotropnim glutamatnim receptorom,[3] GRIK2,[3][4] GRIK3,[3] GRIPAP1,[5] GRIA2[3] i GRIA3.[3]

Reference[уреди]

  1. ^ Bruckner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH, Klein R (April 1999). „EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains“. Neuron 22 (3): 511–24. DOI:10.1016/S0896-6273(00)80706-0. PMID 10197531. 
  2. ^ „Entrez Gene: GRIP1 glutamate receptor interacting protein 1“. 
  3. ^ а б в г д ђ Hirbec, Hélène; Perestenko Olga, Nishimune Atsushi, Meyer Guido, Nakanishi Shigetada, Henley Jeremy M, Dev Kumlesh K (May. 2002). „The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs“. J. Biol. Chem. (United States) 277 (18): 15221–4. DOI:10.1074/jbc.C200112200. ISSN 0021-9258. PMID 11891216. 
  4. ^ Hirbec, Hélène; Francis Joanna C, Lauri Sari E, Braithwaite Steven P, Coussen Françoise, Mulle Christophe, Dev Kumlesh K, Coutinho Victoria, Meyer Guido, Isaac John T R, Collingridge Graham L, Henley Jeremy M, Couthino Victoria (February 2003). „Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP“. Neuron (United States) 37 (4): 625–38. DOI:10.1016/S0896-6273(02)01191-1. ISSN 0896-6273. PMID 12597860. 
  5. ^ Ye, B; Liao D, Zhang X, Zhang P, Dong H, Huganir R L (June 2000). „GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex“. Neuron (UNITED STATES) 26 (3): 603–17. DOI:10.1016/S0896-6273(00)81198-8. ISSN 0896-6273. PMID 10896157. 

Literatura[уреди]