Hinolin 2-oksidoreduktaza
| Hinolin 2-oksidoreduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.99.17 | ||||||||
| CAS broj | 132264-32-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Hinolin 2-oksidoreduktaza (EC 1.3.99.17, hinolinska 2-oksidoreduktaza) je enzim sa sistematskim imenom hinolin:akceptor 2-oksidoreduktaza (hidroksilacija).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hinolin + akceptor +H2O hinolin-2(1H)-on + redukovani akceptor
Hinolin-2-ol, hinolin-7-ol, hinolin-8-ol, 3-, 4- i 8-metilhinolini i 8-hlorohinolin su supstrati. Jodonitrotetrazolijum hlorid može da deluje kao elektronski akceptor.
Reference[уреди | уреди извор]
- ^ Bauder, R., Tshisuaka, B. and Lingens, F. (1990). „Microbial metabolism of quinoline and related compounds. VII. Quinoline oxidoreductase from Pseudomonas putida: a molybdenum-containing enzyme”. Biol. Chem. Hoppe-Seyler. 371: 1137—1144. PMID 2090161.
- ^ Tshisuaka, B., Kappl, R., Huttermann, J. and Lingens, F. (1993). „Quinoline oxidoreductase from Pseudomonas putida 86: an improved purification procedure and electron paramagnetic resonance spectroscopy”. Biochemistry. 32: 12928—12934. PMID 8251516.
- ^ Peschke, B. & Lingens, F. (1991). „Microbial metabolism of quinoline and related compounds. XII. Isolation and characterization of the quinoline oxidoreductase from Rhodococcus sp. B1 compared with the quinoline oxidoreductase from Pseudomonas putida 86”. Biol. Chem. Hoppe-Seyler. 372: 1081—1088. PMID 1789933.
- ^ Schach, S., Tshisuaka, B., Fetzner, S. and Lingens, F. (1995). „Quinoline 2-oxidoreductase and 2-oxo-1,2-dihydroquinoline 5,6-dioxygenase from Comamonas testosteroni 63. The first two enzymes in quinoline and 3-methylquinoline degradation”. Eur. J. Biochem. 232: 536—544. PMID 7556204.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Quinoline+2-oxidoreductase на US National Library of Medicine Medical Subject Headings (MeSH)
