Kalicivirin
| Kalicivirin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.22.66 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Kalicivirin (EC 3.4.22.66, Camberwell virus procesujuća peptidaza, Chiba virus procesujuća peptidaza, Norwalk virus procesujuća peptidaza, Southampton virus procesujuća peptidaza, norovirus virus procesujuća peptidaza, calicivirus tripsinu-slična cisteinska proteaza, calicivirus TCP, calicivirus 3C-slična proteaza, calicivirus endopeptidaza, 3C endopeptidaza virusa bolesti zečje bolesti krvarenja) je enzim.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Endopeptidaza sa a preference for cleavage when the P1 pozicija is occupied by Glu- and the P1' pozicija is occupied by Gly-
Virusi koji su članovi Norovirusnog roda (Caliciviridae familije) su glavni uzrok epidemijskog akutnog viralnog gastroenteritisa.
Reference[уреди | уреди извор]
- ^ Meyers, G., Rossi, C. and Thiel, H.J. (2004). „Calicivirus endopeptidases”. Ур.: Barrett, A.J., Rawlings, N.D. and Woessner, J.F. Handbook of Proteolytic Enzymes (2nd изд.). London: Elsevier. стр. 1380—1382.
- ^ Wirblich, C., Sibilia, M., Boniotti, M.B., Rossi, C., Thiel, H.J. and Meyers, G. (1995). „3C-like protease of rabbit hemorrhagic disease virus: identification of cleavage sites in the ORF1 polyprotein and analysis of cleavage specificity”. J. Virol. 69: 7159—7168. PMID 7474137.
- ^ Martín Alonso, J.M., Casais, R., Boga, J.A. and Parra, F. (1996). „Processing of rabbit hemorrhagic disease virus polyprotein”. J. Virol. 70: 1261—1265. PMID 8551592.
- ^ Liu, B., Clarke, I.N. and Lambden, P.R. (1996). „Polyprotein processing in Southampton virus: identification of 3C-like protease cleavage sites by in vitro mutagenesis”. J. Virol. 70: 2605—2610. PMID 8642693.
- ^ Liu, B.L., Viljoen, G.J., Clarke, I.N. and Lambden, P.R. (1999). „Identification of further proteolytic cleavage sites in the Southampton calicivirus polyprotein by expression of the viral protease in E. coli”. J. Gen. Virol. 80: 291—296. PMID 10073687.
Литература[уреди | уреди извор]
- Meyers, G., Rossi, C. and Thiel, H.J. (2004). „Calicivirus endopeptidases”. Ур.: Barrett, A.J., Rawlings, N.D. and Woessner, J.F. Handbook of Proteolytic Enzymes (2nd изд.). London: Elsevier. стр. 1380—1382.
Spoljašnje veze[уреди | уреди извор]
- Calicivirin на US National Library of Medicine Medical Subject Headings (MeSH)
