Kanabidiolinska kiselina sintaza
| Kanabidiolinska kiselina sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.21.3.8 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Kanabidiolinska kiselina sintaza (EC 1.21.3.8, CBDA sintaza) je enzim sa sistematskim imenom kanabigerolat:kiseonik oksidoreduktaza (ciklizacija, formira kanabidiolat).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- kanabigerolat + O2 kanabidiolat + H2O2
Ovaj enzim kovalentno vezuje FAD. On učestvuje u biosintezi kanabinoida u biljci Cannabis sativa.
Reference[уреди | уреди извор]
- ^ Taura, F., Morimoto, S. and Shoyama, Y. (1996). „Purification and characterization of cannabidiolic-acid synthase from Cannabis sativa L.. Biochemical analysis of a novel enzyme that catalyzes the oxidocyclization of cannabigerolic acid to cannabidiolic acid”. J. Biol. Chem. 271: 17411—17416. PMID 8663284.
- ^ Taura, F., Sirikantaramas, S., Shoyama, Y., Yoshikai, K., Shoyama, Y. and Morimoto, S. (2007). „Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa”. FEBS Lett. 581: 2929—2934. PMID 17544411.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Cannabidiolic+acid+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
