Neurolizin
| Neurolizin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.16 | ||||||||
| CAS broj | 149371-24-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Neurolizin (EC 3.4.24.16, neurotensinska endopeptidaza, endopeptidaza 24.16, endo-oligopeptidaza B, prolinska-endopeptidaza) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Preferentno razlaganje u neurotenzinu: Pro10-Tyr
Ovaj enzim deluje i na pojedine peptide, kao što su dinorfini 1-8, koji ne sadrže prolin.
Reference[уреди | уреди извор]
- ^ Checler, F., Vincent, J.P. and Kitabgi, P. (1986). „Purification and characterization of a novel neurotensin-degrading peptidase from rat brain synaptic membranes”. J. Biol. Chem. 261: 11274—11281. PMID 3525564.
- ^ Barelli, H., Vincent, J.-P. and Checler, F. (1988). „Peripheral inactivation of neurotensin. Isolation and characterization of a metallopeptidase from rat ileum”. Eur. J. Biochem. 175: 481—489. PMID 3409880.
- ^ Checler, F., Barelli, H. and Vincent, J.-P. (1989). „Tissue distribution of a novel neurotensin-degrading metallopeptidase. An immunological approach using monospecific polyclonal antibodies”. Biochem. J. 257: 549—554. PMID 2649078.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Neurolysin на US National Library of Medicine Medical Subject Headings (MeSH)
