Neuromedin N je neuropeptid izveden iz istog prekursornog polipeptida kao i neurotenzin, i sa sličnim ali suptilno različitim izražavanjem i efektima.[2][3][4][5][6][7]
Vidi još [уреди]
Literatura [уреди]
- ^ „Neuromedin N - Compound Summary, PubChem“ .
- ^ Carraway RE, Mitra SP, Spaulding G (1992). „Posttranslational processing of the neurotensin/neuromedin-N precursor“. Annals of the New York Academy of Sciences 668 (1 The Neurobiol): 1–16. DOI:10.1111/j.1749-6632.1992.tb27335.x. PMID 1463268.
- ^ Kitabgi P, De Nadai F, Rovère C, Bidard JN (1992). „Biosynthesis, maturation, release, and degradation of neurotensin and neuromedin N“. Annals of the New York Academy of Sciences 668 (1 The Neurobiol): 30–42. DOI:10.1111/j.1749-6632.1992.tb27337.x. PMID 1463273.
- ^ Vincent JP (October 1995). „Neurotensin receptors: binding properties, transduction pathways, and structure“. Cellular and Molecular Neurobiology 15 (5): 501–12. DOI:10.1007/BF02071313. PMID 8719037.
- ^ Adams DH, Hanson GR, Keefe KA (2001). „Differential effects of cocaine and methamphetamine on neurotensin/neuromedin N and preprotachykinin messenger RNA expression in unique regions of the striatum“. Neuroscience 102 (4): 843–51. DOI:10.1016/S0306-4522(00)00530-3. PMID 11182247.
- ^ Friry C, Feliciangeli S, Richard F, Kitabgi P, Rovere C (February 2002). „Production of recombinant large proneurotensin/neuromedin N-derived peptides and characterization of their binding and biological activity“. Biochemical and Biophysical Research Communications 290 (4): 1161–8. DOI:10.1006/bbrc.2001.6308. PMID 11811984.
- ^ Kitabgi P (October 2006). „Differential processing of pro-neurotensin/neuromedin N and relationship to pro-hormone convertases“. Peptides 27 (10): 2508–14. DOI:10.1016/j.peptides.2006.03.038. PMID 16904237.
Spoljašnje veze [уреди]
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Peptidi: Neuropeptidi |
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| Hormoni |
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| Opioidni peptidi |
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| Drugi neuropeptidi |
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| B trdu: peptidi (nrpl/grfl/cytl/horl), receptori (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd, signalni putevi (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp) |
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Neuropeptidni ligandi |
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| Holecistokinin |
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| CRH |
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| Galanin |
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| Grelin |
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| MCH |
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| Melanokortin |
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| Neuropeptid S |
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| Neuropeptid Y |
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| Neurotenzin |
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| Opioid |
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| Oreksin |
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| Oksitocin |
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| Tahikinin |
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Agonisti: Supstanca P
Antagonisti: Aprepitant • Befetupitant • Kasopitant • CI-1021 • CP-96,345 • CP-99,994 • CP-122,721 • Dapitant • Ezlopitant • FK-888 • Fosaprepitant • GR-203,040 • GW-597,599 • HSP-117 • L-733,060 • L-741,671 • L-743,310 • L-758,298 • Lanepitant • LY-306,740 • Maropitant • Netupitant • NKP-608 • Nolpitantium • Orvepitant • RP-67,580 • SDZ NKT 343 • Vestipitant • Vofopitant
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| Vazopresin |
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