Nitrit reduktaza (formira NO)
| Nitrit reduktaza (formira NO) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Nitrit reduktaza trimer, Alcaligenes faecalis | |||||||||
| Identifikatori | |||||||||
| EC broj | 1.7.2.1 | ||||||||
| CAS broj | 2622511 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Nitrit reduktaza (formira NO) (EC 1.7.2.1, cd-citohrom nitritna reduktaza, citohrom c-551:O2, NO2+ oksidoreduktaza, citohrom cd, citohrom cd1, hidroksilamin (akceptor) reduktaza, metil viologen-nitritna reduktaza, nitritna reduktaza (citohrom, formira NO)) je enzim sa sistematskim imenom nitric-oksid:fericitohrom-c oksidoreduktaza.[1][2][3][4][5][6][7][8][9][10][11] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Azot monoksid +H2O + fericitohrom c nitrit + ferocitohrom c + 2 H+
Ovu reakciju katalizuju dva tipa enzima, koji su prisutni u perimplazmi denitrifikacionih bakterija. Jedan tip obuhvata proteine koji sadrže višestruke bakarne centre, dok su enzimi drugog tipa hem proteini sa citohromom cd1.
Reference[уреди | уреди извор]
- ^ Miyata, M. & Mori, T. (1969). „S'tudies on denitrification. X. The "denitrifying enzyme" as a nitrite reductase and the electron donating system for denitrification”. J. Biochem. (Tokyo). 66: 463—471. PMID 5354021.
- ^ Chung, C.W. & Najjar, V.A. (1956). „Cofactor requirements for enzymatic denitrification. I. Nitrite reductase”. J. Biol. Chem. 218: 617—625. PMID 13295215.
- ^ Walker, G.C. & Nicholas, D.J.D. (1961). „Nitrite reductase from Pseudomonas aeruginosa”. Biochim. Biophys. Acta. 49: 350—360. PMID 13782716.
- ^ Singh, J. (1974). „Cytochrome oxidase from Pseudomonas aeruginosa. III. Reduction of hydroxylamine”. Biochim. Biophys. Acta. 333: 28—36.
- ^ Michalski, W.P. & Nicholas, D.J.D. (1985). „Molecular characterization of a copper-containing nitrite reductase from Rhodopseudomonas sphaeriodes forma sp. Denitrificans”. Biochim. Biophys. Acta. 828: 130—137.
- ^ Godden, J.W., Turley, S., Teller, D.C., Adman, E.T., Liu, M.Y., Payne, W.J. and Legall, J. (1991). „The 2.3 angstrom X-ray structure of nitrite reductase from Achromobacter cycloclastes”. Science. 253: 438—442. PMID 1862344.
- ^ Williams, P.A., Fulop, V., Leung, Y.C., Chan, C., Moir, J.W.B., Howlett, G., Ferguson, S.J., Radford, S.E. and Hajdu, J. (1995). „Pseudospecific docking surfaces on electron transfer proteins as illustrated by pseudoazurin, cytochrome c-550 and cytochrome cd1 nitrite reductase”. Nat. Struct. Biol. 2: 975—982. PMID 7583671.
- ^ Hole, U.H., Vollack, K.U., Zumft, W.G., Eisenmann, E., Siddiqui, R.A., Friedrich, B. and Kroneck, P.M.H. (1996). „Characterization of the membranous denitrification enzymes nitrite reductase (cytochrome cd1) and copper-containing nitrous oxide reductase from Thiobacillus denitrificans”. Arch. Microbiol. 165: 55—61. PMID 8639023.
- ^ Zumft, W.G. (1997). „Cell biology and molecular basis of denitrification”. Microbiol. Mol. Biol. Rev. 61: 533—616. PMID 9409151.
- ^ Ferguson, S.J. (1998). „Nitrogen cycle enzymology”. Curr. Opin. Chem. Biol. 2: 182—193. PMID 9667932.
- ^ Vijgenboom, E., Busch, J.E. and Canters, G.W. (1997). „In vitro studies disprove the obligatory role of azurin in denitrification in Pseudomonas aeruginosa and show that azu expression is under the control of RpoS and ANR”. Microbiology. 143: 2853—2863. PMID 9308169.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Nitrite+reductase+(NO-forming) на US National Library of Medicine Medical Subject Headings (MeSH)
