Pseudouridilatna sintaza
(преусмерено са Pseudouridilat sintaza)
| Pseudouridilatna sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.70 | ||||||||
| CAS broj | 9023-35-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Pseudouridilatna sintaza (EC 4.2.1.70, pseudouridilno kiselinska sintetaza, pseudouridin monofosfatna sintetaza, 5-riboziluracil 5-fosfatna sintetaza, pseudouridilatna sintetaza, upsilonUMP sintetaza, uracilna hidrolijaza (dodaje D-riboza 5-fosfat)) je enzim sa sistematskim imenom uracil hidrolijaza (dodaje D-riboza 5-fosfat, formira pseudouridin-5'-fosfat).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- uracil + D-riboza 5-fosfat pseudouridin 5'-fosfat + H2O
Reference[уреди | уреди извор]
- ^ Heinrikson, R.L. & Goldwasser, E. (1964). „Studies on the biosynthesis of 5-ribosyluracil 5′-monophosphate in Tetrahymena pyriformis”. J. Biol. Chem. 239: 1177—1187. PMID 14165924.
- ^ Matsushita, T. & Davis, F.F. (1971). „Studies on pseudouridylic acid synthetase from various sources”. Biochim. Biophys. Acta. 238: 165—173. PMID 4936431.
- ^ Rensen, J.F., Matsushita, T., Chirikjian, J.G. and Davis, F.F. (1972). „Enzymatic synthesis of deoxypseudouridylic acid and a study of certain of its properties”. Biochim. Biophys. Acta. 281: 481—487. PMID 4569284.
- ^ Suzuki, T. & Hochater, R.M. (1966). „On the biosynthesis of pseudouridine and of pseudouridylic acid in Agrobacterium tumefaciens”. Can. J. Biochem. 44: 259—272. PMID 5942965.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Pseudouridylate+synthase на US National Library of Medicine Medical Subject Headings (MeSH)
