Receptor insulinu sličnog faktora rasta 2

Receptor insulinu sličnog faktora rasta 2‎
PDB prikaz baziran na 1e6f.
Dostupne strukture
1E6F, 1GP0, 1GP3, 1GQB, 1JWG, 1LF8, 2CNJ, 2L29, 2L2A, 2V5N, 2V5O, 2V5P
Identifikatori
Simboli	IGF2R; CD222; CIMPR; M6P-R; MPR1; MPRI
Vanjski ID	OMIM: 147280 MGI: 96435 HomoloGene: 676 GeneCards: IGF2R Gene
Ontologija gena Molekularna funkcija • glikoproteinsko vezivanje • receptorksa aktivnost • aktivnost aktiviranog receptora insulinu sličnog faktora rasta Celularna komponenta • lizozomalna membrana • endozom • integralno sa ćelijskom membranom Biološki proces • receptorom posredovana endocitoza • prenos signala • signalni put receptora insulinu sličnog faktora rasta
Pregled RNK izražavanja
podaci
Ortolozi
Vrsta	Čovek	Miš
Entrez	3482	16004
Ensembl	ENSG00000197081	ENSMUSG00000023830
UniProt	P11717	Q07113
RefSeq (mRNA)	NM_000876.2	NM_010515.2
RefSeq (protein)	NP_000867.2	NP_034645.2
Lokacija (UCSC)	Chr 6: 160.39 - 160.53 Mb	Chr 17: 12.68 - 12.77 Mb
PubMed pretraga	[1]	[2]

Receptor insulinu sličnog faktora rasta 2 (IGF2R, katjionski nezavisni receptor manoza-6-fosfata, CI-MPR) je protein koji je kod ljudi kodiran IGF2R genom. IGF2R je multifunkcionalni proteinski receptor za koji se vezuje insulinu sličan faktor rasta 2 (IGF2) na ćelijskoj površini i manoza-6-fosfat (M6P)-obeležene proteine u trans-Goldžijevom apararu.

Interakcije

Receptor insulinu sličnog faktora rasta 2 formira interakcije sa M6PRBP1.

Literatura

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Vidi još

• Klaster diferencijacije
• Receptor insulinu sličnog faktora rasta 1
• Receptor manoza 6-fosfata

Spoljašnje veze

• MeSH Insulin-Like-Growth-Factor+II+Receptor