UDP-N-acetilmuramat-L-alaninska ligaza
| UDP-N-acetilmuramat-L-alaninska ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.3.2.8 | ||||||||
| CAS broj | 9023-52-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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UDP-N-acetilmuramat-L-alaninska ligaza (EC 6.3.2.8, MurC sintetaza, UDP-N-acetilmuramoil-L-alanin sintetaza, uridin difosfo-N-acetilmuramoilalanin sintetaza, UDP-N-acetilmuramoilalanin sintetaza, enzim dodavanja L-alanina, UDP-acetilmuramil-L-alanin sintetaza, UDPMurNAc-L-alanin sintetaza, L-Ala ligaza, uridin difosfat N-acetilmuramat:L-alanin ligaza, uridin 5'-difosfat-N-acetilmuramil-L-alanin sintetaza, uridin-difosfat-N-acetilmuramat:L-alanin ligaza, UDP-MurNAc:L-alanin ligaza, enzim dodavanja alanina, UDP-N-acetilmuramil:L-alanin ligaza) je enzim sa sistematskim imenom UDP-N-acetilmuramat:L-alanin ligaza (formira ADP).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim učestvuje u sintezi peptida ćelijskog zida.
Reference[уреди | уреди извор]
- ^ Ito, E. & Strominger, J.L. (1962). „Enzymatic synthesis of the peptide in bacterial uridine nucleotides. I. Enzymatic addition of L-alanine, D-glutamic acid, and L-lysine”. J. Biol. Chem. 237: 2689—2695.
- ^ Nathenson, S.G., Strominger, J.L. and Ito, E. (1964). „Enzymatic synthesis of the peptide in bacterial uridine nucleotides. IV. Purification and properties of D-glutamic acid-adding enzyme”. J. Biol. Chem. 239: 1773—1776. PMID 14213349.
- ^ van Heijenoort, J. (2001). „Recent advances in the formation of the bacterial peptidoglycan monomer unit”. Nat. Prod. Rep. 18: 503—519. PMID 11699883.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- UDP-N-acetylmuramate---L-alanine+ligase на US National Library of Medicine Medical Subject Headings (MeSH)
