Malonatna dekarboksilaza nezavisna od biotina
(преусмерено са Biotin-nezavisna malonatna dekarboksilaza)
| Biotin-nezavisna malonatna dekarboksilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.1.88 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Biotin-nezavisna malonatna dekarboksilaza (EC 4.1.1.88, malonat dekarboksilaza (saout biotin), malonat dekarboksilaza, MDC) je enzim sa sistematskim imenom malonat karboksilijaza (biotin-nezavisna).[1][2][3][4][5][6][7][8][9] Ovaj enzim katalizuje sledeću hemijsku reakciju
- malonat + H+ acetat + CO2
Pozanat su dva tipa malonatne dekarboksilaze. Oba su multienzimski kompleksi.
Reference[уреди | уреди извор]
- ^ Schmid, M., Berg, M., Hilbi, H. and Dimroth, P. (1996). „Malonate decarboxylase of Klebsiella pneumoniae catalyses the turnover of acetyl and malonyl thioester residues on a coenzyme-A-like prosthetic group”. Eur. J. Biochem. 237: 221—228. PMID 8620876.
- ^ Byun, H.S. & Kim, Y.S. (1997). „Subunit organization of bacterial malonate decarboxylases: the smallest δ subunit as an acyl-carrier protein”. J. Biochem. Mol. Biol. 30: 132—137.
- ^ Hoenke, S., Schmid, M. and Dimroth, P. (1997). „Sequence of a gene cluster from Klebsiella pneumoniae encoding malonate decarboxylase and expression of the enzyme in Escherichia coli”. Eur. J. Biochem. 246: 530—538. PMID 9208947.
- ^ Chohnan, S., Fujio, T., Takaki, T., Yonekura, M., Nishihara, H. and Takamura, Y. (1998). „Malonate decarboxylase of Pseudomonas putida is composed of five subunits”. FEMS Microbiol. Lett. 169: 37—43. PMID 9851033.
- ^ Hoenke, S., Schmid, M. and Dimroth, P. (2000). „Identification of the active site of phosphoribosyl-dephospho-coenzyme A transferase and relationship of the enzyme to an ancient class of nucleotidyltransferases”. Biochemistry. 39: 13233—13240. PMID 11052676.
- ^ Handa, S., Koo, J.H., Kim, Y.S. and Floss, H.G. (1999). „Stereochemical course of biotin-independent malonate decarboxylase catalysis”. Arch. Biochem. Biophys. 370: 93—96. PMID 10496981.
- ^ Koo, J.H. & Kim, Y.S. (1999). „Functional evaluation of the genes involved in malonate decarboxylation by Acinetobacter calcoaceticus”. Eur. J. Biochem. 266: 683—690. PMID 10561613.
- ^ Kim, Y.S. (2002). „Malonate metabolism: biochemistry, molecular biology, physiology, and industrial application”. J. Biochem. Mol. Biol. 35: 443—451. PMID 12359084.
- ^ Dimroth, P. & Hilbi, H. (1997). „Enzymic and genetic basis for bacterial growth on malonate”. Mol. Microbiol. 25: 3—10. PMID 11902724.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Biotin-independent+malonate+decarboxylase на US National Library of Medicine Medical Subject Headings (MeSH)
