СпоИВБ пептидаза
| SpoIVB peptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.116 | ||||||||
| CAS broj | 296241-18-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
SpoIVB peptidaza (EC 3.4.21.116, proteaza sporulacionog faktora IV B) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Samopresencanje Val52-Asn53, Ala62-Phe63 i Val74-Thr75 na N-terminusu SpoIVB
Ovaj enzim ima centralnu ulogu u regulaciji izražavanja gena tokom kasnijih stupnjeva formiranja spora kod bakterije Bacillus subtilis.
Reference[уреди | уреди извор]
- ^ Wakeley, P.R., Dorazi, R., Hoa, N.T., Bowyer, J.R. and Cutting, S.M. (2000). „Proteolysis of SpolVB is a critical determinant in signalling of pro-σK processing in Bacillus subtilis”. Mol. Microbiol. 36: 1336—1348. PMID 10931284.
- ^ Hoa, N.T., Brannigan, J.A. and Cutting, S.M. (2001). „The PDZ domain of the SpoIVB serine peptidase facilitates multiple functions”. J. Bacteriol. 183: 4364—4373. PMID 11418578.
- ^ Hoa, N.T., Brannigan, J.A. and Cutting, S.M. (2002). „The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases”. J. Bacteriol. 184: 191—199. PMID 11741860.
- ^ Dong, T.C. & Cutting, S.M. (2003). „SpoIVB-mediated cleavage of SpoIVFA could provide the intercellular signal to activate processing of pro-σK in Bacillus subtilis”. Mol. Microbiol. 49: 1425—1434. PMID 12940997.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- SpoIVB+peptidase на US National Library of Medicine Medical Subject Headings (MeSH)
