Akonitaza
| Akonitat hidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Ilustracija akonitaze svinje u kompleksu sa [Fe4S4] klusterom.[1] | |||||||||
| Identifikatori | |||||||||
| EC broj | 4.2.1.3 | ||||||||
| CAS broj | 9024-25-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBsum | ||||||||
| Ontologija gena | AmiGO / EGO | ||||||||
| |||||||||
Akonitaza je trivijalni naziv za gvožđe-sumporni enzim akonitat hidratazu (citrat hidrolijazu, EC 4.2.1.3) koji katalizuje reverzibilne reakcije stereospecifične izomerizacije citrata, cis-akonitata i izocitrata u Krebsovom ciklusu.[2][3][4]
Reference[uredi | uredi izvor]
- ^ PDB: 7ACN; Lauble, H.; Kennedy, M. C.; Beinert, H.; Stout, C. D. (1992). „Crystal structures of aconitase with isocitrate and nitroisocitrate bound”. Biochemistry. 31 (10): 2735—48. PMID 1547214. doi:10.1021/bi00125a014.
- ^ Beinert, H; Kennedy, MC (1993). „Aconitase, a two-faced protein: Enzyme and iron regulatory factor”. The FASEB Journal. 7 (15): 1442—9. PMID 8262329.
- ^ Flint, Dennis H.; Allen, Ronda M. (1996). „Iron−Sulfur Proteins with Nonredox Functions”. Chemical Reviews. 96 (7): 2315—34. doi:10.1021/cr950041r.
- ^ Beinert, Helmut; Kennedy, Mary Claire; Stout, C. David (1996). „Aconitase as Iron−Sulfur Protein, Enzyme, and Iron-Regulatory Protein”. Chemical Reviews. 96 (7): 2335—74. PMID 11848830. doi:10.1021/cr950040z.
Literatura[uredi | uredi izvor]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
