Ekvilibrativni nukleozidni transporter
| Purinergična signalizacija |
|---|
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| Koncepti |
| Membranski transporteri |
Ekvilibrativni nukleozidni transporter (ENT familija, SLC29) je grupa membranskih transportnih proteina koji transportuju nukleozidne supstrate poput adenozina u ćelije.[1] Poznata su četiri ENT proteina: ENT1, ENT2, ENT3, i ENT4.[1][2] ENT proteini se blokiraju inhibitorima preuzimanja adenozina kao što su dipiridamol i dilazep, lekovima sa kliničkom primenom kao vazodilatatori.[2][3]
Reference[uredi | uredi izvor]
- ^ a b Baldwin SA, Beal PR, Yao SY, King AE, Cass CE, Young JD (2004). „The equilibrative nucleoside transporter family, SLC29”. Pflügers Archiv : European Journal of Physiology. 447 (5): 735—43. PMID 12838422. doi:10.1007/s00424-003-1103-2.
- ^ a b Molina-Arcas M, Casado FJ, Pastor-Anglada M (2009). „Nucleoside transporter proteins”. Current Vascular Pharmacology. 7 (4): 426—34. PMID 19485885. Arhivirano iz originala 13. 01. 2013. g. Pristupljeno 05. 10. 2020.
- ^ Noji T, Karasawa A, Kusaka H (2004). „Adenosine uptake inhibitors”. European Journal of Pharmacology. 495 (1): 1—16. PMID 15219815. doi:10.1016/j.ejphar.2004.05.003.
Literatura[uredi | uredi izvor]
- Molina-Arcas M, Casado FJ, Pastor-Anglada M (2009). „Nucleoside Transporter Proteins”. Current Vascular Pharmacology. 7 (4): 426—34. PMID 19485885. Arhivirano iz originala 13. 01. 2013. g. Pristupljeno 05. 10. 2020.
- Baldwin SA, Beal PR, Yao SY, King AE, Cass CE, Young JD (2004). „The equilibrative nucleoside transporter family, SLC29”. Pflügers Archiv : European Journal of Physiology. 447 (5): 735—43. PMID 12838422. doi:10.1007/s00424-003-1103-2.
- Molina-Arcas M, Trigueros-Motos L, Casado FJ, Pastor-Anglada M (2008). „Physiological and pharmacological roles of nucleoside transporter proteins”. Nucleosides, Nucleotides & Nucleic Acids. 27 (6): 769—78. PMID 18600539. doi:10.1080/15257770802145819.