Fenilpiperazin

Fenilpiperazin
Nazivi
	IUPAC naziv 1-phenylpiperazine
Identifikacija
CAS broj	92-54-6;
3D model (Jmol)	interaktivna slika;
ChemSpider	6829;
ECHA InfoCard	100.001.969
PubChem C ID	7096;
	SMILES c1cc(ccc1)N2CCNCC2; ; ; ; ; ;
Svojstva
Hemijska formula	C10H14N2
Molarna masa	162,23 g/mol
Agregatno stanje	čista bezbojna do žute tečnosti
Gustina	1,028g/cm3
Tačka topljenja	18.8°C
Tačka ključanja	287.2°C @ 760mmHg
Rastvorljivost u vodi	nerastvoran
Opasnosti
Tačka paljenja	138.3°C
	Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
	Reference infokutije

1-Fenilpiperazin je jednostavno hemijsko jedinjenje koje sadrži fenilna grupa:fenilnu grupu vezanu za piperazinski prsten. Sufiks '-piprazol' se ponekad koristi u imenima lekova da se naznači da pripadaju ovoj klasi.^[3]^[4]

Brojni fenilpiperazinski derivati su lekovi. Neki od njih su:

Lekovi
- Antrafenin - Antiinflamatorni lek
- Aripiprazol - Antipsihotik
- Ciprofloksacin - Antibiotic
- Dapiprazol - Alfa blokator
- Dropropizin - Antitusiv
- Etoperidon - Antidepresiv
- Itrakonazol - Antifungal
- Ketokonazol - Antifungal
- Levodropropizin - Antitusiv
- Mepiprazol - Anksiolitik
- Naftopidil - Antihipertenziv
- Nefazodon - Antidepresiv
- Niaprazin - Hipnotik
- Oksipertin - Antipsihotik
- Posakonazol - Antifungal
- Trazodon - Antidepresiv
- Urapidil - Antihipertenziv
- Vesnarinon - Kardiotonik
Istraživačke hemikalije
- Akaprazin - Anksiolytik
- Batoprazin - Serenik
- Bifeprunoks - Antipsihotik
- BRL-15,572 - Serotonergik
- CSP-2503 - Anksiolitik
- DMPP - Nikotinik
- EGIS-12,233 - Serotonergik
- Elopiprazol - Antipsihotik
- Eltoprazin - Serenik
- Enpiprazol - Anksiolitik
- Ensakulin - Nootropik
- Flibanserin - Afrodizijak
- Fluprazin - Serenik
- Flesinoksan - Antidepresiv
- Lorpiprazol - Anksiolitik
- Naftilpiperazin - Serotonergik
- Pardoprunoks - Antiparkinsonijan
- PRX-00023 - Antidepresiv
- S-14,506 - Serotonergik
- S-14,671 - Serotonergik
- S-15,535 - Serotonergik
- SB-258,585 - Serotonergik
- SB-271,046 - Serotonergik
- SB-357,134 - Serotonergik
- SB-399,885 - Serotonergik
- Sonepiprazol - Dopaminergik
- Tolpiprazol - Anksiolitik
- Vilazodon - Antidepresiv
- WAY-100,135 - Serotonergik
- WAY-100,635 - Serotonergik
Lekovi u razvoju
- DCPP - Serotonergik
- mCPP - Serotonergik
- MeOPP - Serotonergik
- pCPP - Serotonergic
- pFPP - Serotonergic
- TFMPP - Serotonergik

Vidi još[uredi | uredi izvor]

Reference[uredi | uredi izvor]

^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. уреди
^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.
^ World Health Organization (WHO) (2006). „The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances” (PDF). Приступљено 1. 1. 2010.
^ Keith Parker; Laurence Brunton; Goodman, Louis Sanford; Lazo, John S.; Gilman, Alfred (2006). Goodman & Gilman's The Pharmacological Basis of Therapeutics (11. изд.). New York: McGraw-Hill. ISBN 0071422803.

Literatura[uredi | uredi izvor]

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. уреди

[2] Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1.

[The_use_of_stems_in_the_selection_of_International_Nonproprietary_Names_(INN)_for_pharmaceutical_substances-3] World Health Organization (WHO) (2006). „The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances” (PDF). Приступљено 1. 1. 2010.

[4] Keith Parker; Laurence Brunton; Goodman, Louis Sanford; Lazo, John S.; Gilman, Alfred (2006). Goodman & Gilman's The Pharmacological Basis of Therapeutics (11. изд.). New York: McGraw-Hill. ISBN 0071422803.

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