Manozil-oligosaharid 1,2-alfa-manozidaza
| Manozil-oligosaharid 1,2-alfa-manozidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.2.1.113 | ||||||||
| CAS broj | 9068-25-1 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Manozil-oligosaharid 1,2-alfa-manozidaza (EC 3.2.1.113, manozidaza 1A, manozidaza 1B, 1,2-alfa-manozidaza, ekso-alfa-1,2-mananaza, manoza-9 alfa-manozidaza, glikoproteinska manozidaza I, manozidaza I, Man9-manozidaza, ManI, 1,2-alfa-manozil-oligosaharid alfa-D-manohidrolaza) je enzim sa sistematskim imenom 2-alfa-manozil-oligosaharid alfa-D-manohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hidroliza terminalnih (1->2)-vezanih alfa-D-manoznih ostataka u oligo-manoznom oligosaharidu Man9(GlcNAc)2
Ovaj enzim učestvuje u sintezi glikoproteina.
Reference[uredi | uredi izvor]
- ^ Tabas, I. & Kornfeld, S. (1979). „Purification and characterization of a rat liver Golgi α-mannosidase capable of processing asparagine-linked oligosaccharides”. J. Biol. Chem. 254: 11655—11663. PMID 500665.
- ^ Tulsiani, D.R.P., Hubbard, S.C., Robbins, P.W. and Touster, O. (1982). „α-D-Mannosidases of rat liver Golgi membranes. Mannosidase II is the GlcNAcMAN5-cleaving enzyme in glycoprotein biosynthesis and mannosidases IA and IB are the enzymes converting Man9 precursors to Man5 intermediates”. J. Biol. Chem. 257: 3660—3668. PMID 7061502.
Literatura[uredi | uredi izvor]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[uredi | uredi izvor]
- Mannosyl-oligosaccharide+1,2-alpha-mannosidase na US National Library of Medicine Medical Subject Headings (MeSH)
