Mutaza
Mutaza je enzim iz klase izomeraza koji katalizuje prelaz funkcionalne grupe iz jedne pozicije u drugu unutar istog molekula.[1][2] Primeri enzima ove grupe su bisfosfogliceratna mutaza,[3] koja je prisutna u crvenim krvnim zrncima i fosfogliceratna mutaza, koja učestvuje u glikolizi, gde menja 3-fosfoglicerat u 2-fosfoglicerat. Ona menja poziciju fosfatne grupe.
Reference[уреди | уреди извор]
- ^ Donald Voet; Judith G. Voet (2005). Biochemistry (3 изд.). Wiley. ISBN 9780471193500.
- ^ David L. Nelson; Michael M. Cox (2005). Principles of Biochemistry (IV изд.). New York: W. H. Freeman. ISBN 0-7167-4339-6.
- ^ PDB: 1T8P; Wang Y, Wei Z, Bian Q, Cheng Z, Wan M, Liu L, Gong W (2004). „Crystal structure of human bisphosphoglycerate mutase”. J. Biol. Chem. 279 (37): 39132—8. PMID 15258155. doi:10.1074/jbc.M405982200.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
