Ruberlizin
| Ruberlizin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.48 | ||||||||
| CAS broj | 846020-01-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ruberlizin (EC 3.4.24.48, Crotalus ruber metaloendopeptidaza II, hemoragični toksin II) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Razlaganje His10-Leu, Ala14-Leu, Tyr16-Leu i Gly23-Phe veza B lancu insulina; His-Pro, Pro-Phe, i Trp-Ser angiotenzina I; i Gly-Phe u Met enkefalinu
Ova hemoragična endopeptidaza je prisutna u venumu zvečarke Crotalus ruber ruber.
Reference[уреди | уреди извор]
- ^ Mori, N., Nikai, T., Sugihara, H. and Tu, A.T. (1987). „Biochemical characterization of hemorrhagic toxins with fibrinogenase activity isolated from 'Crotalus ruber ruber venom”. Arch. Biochem. Biophys. 253: 108—121. PMID 2949699.
- ^ Takeya, H., Onikura, A., Nikai, T., Sugihara, H. and Iwanaga, S. Primary structure of a hemorrhagic metalloproteinase, HT- (1990). „2, isolated from the venom of Crotalus ruber ruber”. J. Biochem. (Tokyo). 108: 711—719. PMID 2081731.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Ruberlysin на US National Library of Medicine Medical Subject Headings (MeSH)
