2,4-Dienoil-KoA reduktaza (NADPH)
| 2,4-dienoil-KoA reduktaza (NADPH) | |||||||||
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| Identifikatori | |||||||||
| EC broj | 1.3.1.34 | ||||||||
| CAS broj | 82869-38-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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2,4-dienoil-KoA reduktaza (NADPH) (EC 1.3.1.34, 4-enoil-KoA reduktaza (NADPH), 4-enoil koenzim A (redukovani nikotinamid adenin dinukleotid fosfat) reduktaza, 4-enoil-KoA reduktaza) je enzim sa sistematskim imenom trans-2,3-didehidroacil-KoA:NADP+ 4-oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- trans-2,3-didehidroacil-KoA + NADP+ trans,trans-2,3,4,5-tetradehidroacil-KoA + NADPH + H+
Najbolji supstrati ove redukcije sadrže 2,4-diensku strukturu i imaju lanac dug 8 ili 10 ugljenika.
Reference[уреди | уреди извор]
- ^ Dommes, V., Luster, W., Cvetanovic, M. and Kunau, W.-H. (1982). „Purification by affinity chromatography of 2,4-dienoyl-CoA reductases from bovine liver and Escherichia coli”. Eur. J. Biochem. 125: 335—341. PMID 6749495.
- ^ Kunau, W.-H. & Dommes, P. (1978). „Degradation of unsaturated fatty acids. Identification of intermediates in the degradation of cis-4-decenoly-CoA by extracts of beef-liver mitochondria”. Eur. J. Biochem. 91: 533—544. PMID 729581.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- 2,4-dienoyl-CoA+reductase+(NADPH) на US National Library of Medicine Medical Subject Headings (MeSH)
