2-Aminomukonatna deaminaza
| 2-Aminomukonatna deaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.99.5 | ||||||||
| CAS broj | 201098-29-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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2-Aminomukonatna deaminaza (EC 3.5.99.5, amnD (gen), nbaF (gen)) je enzim sa sistematskim imenom 2-aminomukonat aminohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 2-aminomukonat + H2O (3E)-2-oksoheks-3-endioat + NH3
2-Aminomukonat je intermedijer u bakterijskoj biodegradaciji nitrobenzena.
Reference[уреди | уреди извор]
- ^ He, Z & Spain, J.C. (1997). „Studies of the catabolic pathway of degradation of nitrobenzene by Pseudomonas pseudoalcaligenes JS45: removal of the amino group from 2-aminomuconic semialdehyde”. Appl. Environ. Microbiol. 63: 4839—4843. PMID 9471964.
- ^ He, Z. & Spain, J.C. (1998). „A novel 2-aminomuconate deaminase in the nitrobenzene degradation pathway of Pseudomonas pseudoalcaligenes JS45”. J. Bacteriol. 180: 2502—2506. PMID 9573204.
- ^ Takenaka, S., Murakami, S., Kim, Y.J. and Aoki, K. (2000). „Complete nucleotide sequence and functional analysis of the genes for 2-aminophenol metabolism from Pseudomonas sp. AP-3”. Arch. Microbiol. 174: 265—272. PMID 11081795.
- ^ Muraki, T., Taki, M., Hasegawa, Y., Iwaki, H. and Lau, P.C. (2003). „Prokaryotic homologs of the eukaryotic 3-hydroxyanthranilate 3,4-dioxygenase and 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase in the 2-nitrobenzoate degradation pathway of Pseudomonas fluorescens strain KU-7”. Appl. Environ. Microbiol. 69: 1564—1572. PMID 12620844.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- 2-aminomuconate+deaminase на US National Library of Medicine Medical Subject Headings (MeSH)
