5-Fosfonooksi-L-lizinska fosfo-lijaza
| 5-Fosfonooksi-L-lizinska fosfo-lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.3.134 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
5-Fosfonooksi-L-lizinska fosfo-lijaza (EC 4.2.3.134, 5-fosfohidroksi-L-lizin amoniofosfolijaza, AGXT2L2 (gen)) je enzim sa sistematskim imenom (5R)-5-fosfonooksi-L-lizin fosfat-lijaza (deaminacija, formira (S)-2-amino-6-oksoheksanoat).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (5R)-5-fosfonooksi-L-lizin +H2O (S)-2-amino-6-oksoheksanoat + NH3 + fosfat
Ovaj enzim je piridoksal-fosfatni protein.
Reference[уреди | уреди извор]
- ^ Tsai, C.H. & Henderson, L.M. (1974). „Degradation of O-phosphohydroxylysine by rat liver. Purification of the phospho-lyase”. J. Biol. Chem. 249: 5784—5789. PMID 4412716.
- ^ Veiga-da-Cunha, M., Hadi, F., Balligand, T., Stroobant, V. and Van Schaftingen, E. (2012). „Molecular identification of hydroxylysine kinase and of ammoniophospholyases acting on 5-phosphohydroxy-L-lysine and phosphoethanolamine”. J. Biol. Chem. 287: 7246—7255. PMID 22241472.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- 5-phosphonooxy-L-lysine+phospho-lyase на US National Library of Medicine Medical Subject Headings (MeSH)
