С Википедије, слободне енциклопедије
Bupivakain Prodajno ime Anekain, Bupivan, Carbostesin, Marcaina Drugs.com Monografija Način primene Intraspinalno Poluvreme eliminacije 2,7 h Izlučivanje Renalno
CAS broj 2180-92-9 Y ATC kod N01BB01 (WHO N01 BB10 PubChem CID 2474 IUPHAR/BPS 2397 DrugBank DB00297 Y ChemSpider 2380 Y KEGG C07529 Y ChEBI CHEBI:3215 Y ChEMBL CHEMBL1098 Y Formula C 18 H 28 N 2 O Molarna masa 288,428
CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C
InChI=1S/C18H28N2O/c1-4-5-12-20-13-7-6-11-16(20)18(21)19-17-14(2)9-8-10-15(17)3/h8-10,16H,4-7,11-13H2,1-3H3,(H,19,21)
Y Key:LEBVLXFERQHONN-UHFFFAOYSA-N
Y
Tačka topljenja
Bupivakain je organsko jedinjenje , koje sadrži 18 atoma ugljenika i ima molekulsku masu od 288,428 Da .[1] [2] [3] [4]
^ Rosenblatt MA, Abel M, Fischer GW, Itzkovich CJ, Eisenkraft JB: Successful use of a 20% lipid emulsion to resuscitate a patient after a presumed bupivacaine-related cardiac arrest. Anesthesiology. 2006 Jul;105(1):217-8. PMID 16810015
^ Picard J, Meek T: Lipid emulsion to treat overdose of local anaesthetic: the gift of the glob. Anaesthesia. 2006 Feb;61(2):107-9. PMID 16430560
^ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs” . Nucleic Acids Res . 39 (Database issue): D1035—41. PMC 3013709 PMID 21059682 . doi :10.1093/nar/gkq1126 . ^ David S. Wishart; Craig Knox; An Chi Guo; Dean Cheng; Savita Shrivastava; Dan Tzur; Bijaya Gautam; Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets” . Nucleic acids research . 36 (Database issue): D901—6. PMC 2238889 PMID 18048412 . doi :10.1093/nar/gkm958 . ^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods” . J. Phys. Chem. A . 102 : 3762—3772. doi :10.1021/jp980230o . ^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices” . Chem Inf. Comput. Sci . 41 : 1488—1493. PMID 11749573 . doi :10.1021/ci000392t . ^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties” . J. Med. Chem . 43 : 3714—3717. PMID 11020286 . doi :10.1021/jm000942e .
Molimo Vas, obratite pažnju na važno upozorenje oblasti medicine (zdravlja) .
. PMID 21059682. doi:10.1093/nar/gkq1126.
