D-dopahromna dekarboksilaza
| D-dopahromna dekarboksilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.1.84 | ||||||||
| CAS broj | 184111-06-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
D-dopahromna dekarboksilaza (EC 4.1.1.84, fenilpiruvatna tautomeraza II, D-tautomeraza, D-dopahromna tautomeraza, D-dopahromna karboksilijaza) je enzim sa sistematskim imenom D-dopachrome karboksilijaza (formira 5,6-dihidroksiindol).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- D-dopahrom 5,6-dihidroksiindol + CO2
Ovaj enzim je specifičan za D-dopahrom kao supstrat.
Reference[уреди | уреди извор]
- ^ Odh, G., Hindemith, A., Rosengren, A.M., Rosengren, E. and Rorsman, H. (1993). „Isolation of a new tautomerase monitored by the conversion of D-dopachrome to 5,6-dihydroxyindole”. Biochem. Biophys. Res. Commun. 197: 619—624. PMID 8267597.
- ^ Yoshida, H., Nishihira, J., Suzuki, M. and Hikichi, K. (1997). „NMR characterization of physicochemical properties of rat D-dopachrome tautomerase”. Biochem. Mol. Biol. Int. 42: 891—899. PMID 9285056.
- ^ Sugimoto, H., Taniguchi, M., Nakagawa, A., Tanaka, I., Suzuki, M. and Nishihira, J. (1999). „Crystal structure of human D-dopachrome tautomerase, a homologue of macrophage migration inhibitory factor, at 1.54 Å resolution”. Biochemistry. 38: 3268—3279. PMID 10079069.
- ^ Nishihira, J., Fujinaga, M., Kuriyama, T., Suzuki, M., Sugimoto, H., Nakagawa, A., Tanaka, I. and Sakai, M. (1998). „Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation”. Biochem. Biophys. Res. Commun. 243: 538—544. PMID 9480844.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- D-dopachrome+decarboxylase на US National Library of Medicine Medical Subject Headings (MeSH)
