EMR receptor

EGF modul sadržavajući, mucinu sličan, hormonski receptor 3
EGF modul sadržavajući, mucinu sličan, hormonski receptor 3
Identifikatori
Simbol	EMR3
IUPHAR	EMR3
Entrez	84658
HUGO	23647
OMIM	606101
RefSeq	NM_032571
UniProt	Q9BY15
Ostali podaci
Lokus	Hromozom 19 p13.1

EGF modul sadržavajući, mucinu sličan, hormonski receptor 2
EGF modul sadržavajući, mucinu sličan, hormonski receptor 2
Identifikatori
Simbol	EMR2
IUPHAR	EMR2
Entrez	30817
HUGO	3337
OMIM	606100
RefSeq	NM_152916
UniProt	Q9UHX3
Ostali podaci
Lokus	Hromozom 19 p13.1

EGF modul sadržavajući, mucinu sličan, hormonski receptor 1
EGF modul sadržavajući, mucinu sličan, hormonski receptor 1
Identifikatori
Simbol	EMR1
Alt. simboli	TM7LN3
IUPHAR	EMR1
Entrez	2015
HUGO	3336
OMIM	600493
RefSeq	NM_001974
UniProt	Q14246
Ostali podaci
Lokus	Hromozom 19 p13.3

EGF modul sadržavajući, mucinu sličan, hormonski receptori (EMR) su blisko srodna grupa G protein spregnutih receptora. Ti receptori imaju jedinstvene hibridne strukture u kojima su ekstracelularni domeni slični epidermalnom faktoru rasta spojeni sa GPCR domenom putem mucinu sličnog segmenta.^[1]^[2]^[3]^[4]

Postoje četiri varijante EMR receptora, koje se obležavanju sa 1-4. One su kodirane zasebnim genima. Ti receptori su predominatno izraženi u ćelijama ljudskog imunskog sistema i za njih se vezuju ligandi poput CD55.^[5]

EGF modul sadržavajući, mucinu sličan, hormonski receptor 4 pseudogen
Identifikatori
Simbol	EMR4P
Alt. simboli	GPR127
Entrez	326342
HUGO	19240
RefSeq	XM_940358
UniProt	Q86SQ3
Ostali podaci
Lokus	Hromozom 19 p13.3

Reference

^ Baud V, Chissoe SL, Viegas-Péquignot E, Diriong S, N'Guyen VC, Roe BA, Lipinski M (1995). . „EMR1, an unusual member in the family of hormone receptors with seven transmembrane segments”. Genomics. 26 (2): 334—44. PMID 7601460. doi:10.1016/0888-7543(95)80218-B.
^ Lin HH, Stacey M, Hamann J, Gordon S, McKnight AJ (2000). . „Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97”. Genomics. 67 (2): 188—200. PMID 10903844. doi:10.1006/geno.2000.6238.
^ Stacey M, Lin HH, Hilyard KL, Gordon S, McKnight AJ (2001). . „Human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 is a new member of the EGF-TM7 family that recognizes a ligand on human macrophages and activated neutrophils”. J. Biol. Chem.. 276 (22): 18863—70. PMID 11279179. doi:10.1074/jbc.M101147200.
^ Caminschi I, Vandenabeele S, Sofi M, McKnight AJ, Ward N, Brodnicki TC, Toy T, Lahoud M, Maraskovsky E, Shortman K, Wright MD (2006). . „Gene structure and transcript analysis of the human and mouse EGF-TM7 molecule, FIRE”. DNA Seq.. 17 (1): 8—14. PMID 16753812. doi:10.1080/10425170500355737.
^ Kwakkenbos MJ, Kop EN, Stacey M, Matmati M, Gordon S, Lin HH, Hamann J (2004). . „The EGF-TM7 family: a postgenomic view”. Immunogenetics. 55 (10): 655—66. PMID 14647991. doi:10.1007/s00251-003-0625-2.

Spoljašnje veze

EMR1+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
EMR2+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
EMR3+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)
EMR4+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)

[pmid7601460-1] Baud V, Chissoe SL, Viegas-Péquignot E, Diriong S, N'Guyen VC, Roe BA, Lipinski M (1995). . „EMR1, an unusual member in the family of hormone receptors with seven transmembrane segments”. Genomics. 26 (2): 334—44. PMID 7601460. doi:10.1016/0888-7543(95)80218-B.

[pmid10903844-2] Lin HH, Stacey M, Hamann J, Gordon S, McKnight AJ (2000). . „Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97”. Genomics. 67 (2): 188—200. PMID 10903844. doi:10.1006/geno.2000.6238.

[pmid11279179-3] Stacey M, Lin HH, Hilyard KL, Gordon S, McKnight AJ (2001). . „Human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 is a new member of the EGF-TM7 family that recognizes a ligand on human macrophages and activated neutrophils”. J. Biol. Chem.. 276 (22): 18863—70. PMID 11279179. doi:10.1074/jbc.M101147200.

[pmid16753812-4] Caminschi I, Vandenabeele S, Sofi M, McKnight AJ, Ward N, Brodnicki TC, Toy T, Lahoud M, Maraskovsky E, Shortman K, Wright MD (2006). . „Gene structure and transcript analysis of the human and mouse EGF-TM7 molecule, FIRE”. DNA Seq.. 17 (1): 8—14. PMID 16753812. doi:10.1080/10425170500355737.

[pmid14647991-5] Kwakkenbos MJ, Kop EN, Stacey M, Matmati M, Gordon S, Lin HH, Hamann J (2004). . „The EGF-TM7 family: a postgenomic view”. Immunogenetics. 55 (10): 655—66. PMID 14647991. doi:10.1007/s00251-003-0625-2.

[1]

[2]

[3]

[4]

[5]