Fas-aktivirana serin/treonin kinaza
| Fas-aktivirana serin/treonin kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.11.8 | ||||||||
| CAS broj | 170347-50-9 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Fas-aktivirana serin/treonin kinaza (EC 2.7.11.8, FAST, FASTK, STK10) je enzim sa sistematskim imenom ATP:(Fas-aktivirani serin/treonin protein) fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim se aktivira tokom Fas-posredovane apoptoze.
Reference[уреди | уреди извор]
- ^ Tian, Q., Taupin, J., Elledge, S., Robertson, M. and Anderson, P. (1995). „Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis”. J. Exp. Med. 182: 865—874. PMID 7544399.
- ^ Li, W., Simarro, M., Kedersha, N. and Anderson, P. (2004). „FAST is a survival protein that senses mitochondrial stress and modulates TIA-1-regulated changes in protein expression”. Mol. Cell. Biol. 24: 10718—10732. PMID 15572676.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Fas-activated+serine/threonine+kinase на US National Library of Medicine Medical Subject Headings (MeSH)
