Fosfoetanolamin/fosfoholinska fosfataza
(преусмерено са Fosfoetanolamin/fosfoholin fosfataza)
| Fosfoetanolamin/fosfoholinska fosfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.3.75 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Fosfoetanolamin/fosfoholinska fosfataza (EC 3.1.3.75, PHOSPHO1, 3X11A) je enzim sa sistematskim imenom fosfoetanolamin fosfohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (1) O-fosfoeetanolamin + H2O etanolamin + fosfat
- (2) fosfoholin + H2O holin + fosfat
Za rad ovog enzim je neophodan Mg2+.
Reference[уреди | уреди извор]
- ^ Houston, B., Seawright, E., Jefferies, D., Hoogland, E., Lester, D., Whitehead, C. and Farquharson, C. (1999). „Identification and cloning of a novel phosphatase expressed at high levels in differentiating growth plate chondrocytes”. Biochim. Biophys. Acta. 1448: 500—506. PMID 9990301.
- ^ Stewart, A.J., Schmid, R., Blindauer, C.A., Paisey, S.J. and Farquharson, C. (2003). „Comparative modelling of human PHOSPHO1 reveals a new group of phosphatases within the haloacid dehalogenase superfamily”. Protein Eng. 16: 889—895. PMID 14983068.
- ^ Roberts, S.J., Stewart, A.J., Sadler, P.J. and Farquharson, C. (2004). „Human PHOSPHO1 displays high specific phosphoethanolamine and phosphocholine phosphatase activities”. Biochem. J. 382: 59—65. PMID 15175005.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Phosphoethanolamine/phosphocholine+phosphatase на US National Library of Medicine Medical Subject Headings (MeSH)
