GABRR3

GABRR3
Identifikatori
Alijasi	GABRR3
Spoljašnji ID	MGI: 3588203 HomoloGene: 26716 GeneCards: GABRR3
Genska lokacija (miš)
Hr.	Chromosome 16 (mouse)
Kraj	59,284,867 bp
Genska ontologija
Molecular function	• chloride channel activity; • GABA-A receptor activity; • extracellular ligand-gated ion channel activity; • ion channel activity; • transmembrane signaling receptor activity; • protein domain specific binding;
Cellular component	• мембрана; • саставни део мембране; • cell junction; • GABA-A receptor complex; • ћелијска мембрана; • postsynaptic membrane; • синапса; • chloride channel complex; • ћелијски састојак; • integral component of plasma membrane; • neuron projection;
Biological process	• gamma-aminobutyric acid signaling pathway; • chloride transport; • chloride transmembrane transport; • ion transport; • chemical synaptic transmission; • ion transmembrane transport; • GO:0072468 Prenos signala; • regulation of membrane potential; • процес нервног система;
	Sources:Amigo / QuickGO
Ortolozi
	200959
	328699
	ENSG00000183185
	ENSMUSG00000074991
	A8MPY1
	B2RXA8
	NM_001105580
	NM_001081190
	NP_001099050
	NP_001074659
	Wikidata
View/Edit Human	View/Edit Mouse

Receptor gama-aminobutirne kiseline, podjedinica ro-3 je protein koji je kod ljudi kodiran GABRR3 genom.^[4] Protein kodiran ovim genom je podjecinica GABA_A-ρ receptora.

Vidi još[уреди | уреди извор]

GABA_A-ρ receptor

Reference[уреди | уреди извор]

^ ^а ^б ^в GRCm38: Ensembl release 89: ENSMUSG00000074991 - Ensembl, May 2017
^ „Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ „Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bailey ME, Albrecht BE, Johnson KJ, Darlison MG (1999). „Genetic linkage and radiation hybrid mapping of the three human GABA(C) receptor rho subunit genes: GABRR1, GABRR2 and GABRR3”. Biochim. Biophys. Acta. 1447 (2–3): 307—12. PMID 10542332. doi:10.1016/S0167-4781(99)00167-0.

Literatura[уреди | уреди извор]

Croci C, Brändstatter JH, Enz R (2003). „ZIP3, a new splice variant of the PKC-zeta-interacting protein family, binds to GABAC receptors, PKC-zeta, and Kv beta 2”. J. Biol. Chem. 278 (8): 6128—35. PMID 12431995. doi:10.1074/jbc.M205162200.
Craddock N, Jones L, Jones IR, et al. (2010). „Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype”. Mol. Psychiatry. 15 (2): 146—53. PMID 19078961. doi:10.1038/mp.2008.66.
Alakuijala A, Palgi M, Wegelius K, et al. (2005). „GABA receptor rho subunit expression in the developing rat brain”. Brain Res. Dev. Brain Res. 154 (1): 15—23. PMID 15617751. doi:10.1016/j.devbrainres.2004.09.010.
Bailey ME, Albrecht BE, Johnson KJ, Darlison MG (1999). „Genetic linkage and radiation hybrid mapping of the three human GABA(C) receptor rho subunit genes: GABRR1, GABRR2 and GABRR3”. Biochim. Biophys. Acta. 1447 (2–3): 307—12. PMID 10542332. doi:10.1016/S0167-4781(99)00167-0.
Gratacòs M, Costas J, de Cid R, et al. (2009). „Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment”. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6): 808—16. PMID 19086053. doi:10.1002/ajmg.b.30902.
Muzny DM, Scherer SE, Kaul R, et al. (2006). „The DNA sequence, annotation and analysis of human chromosome 3”. Nature. 440 (7088): 1194—8. PMID 16641997. doi:10.1038/nature04728.

Spoljašnje veze[уреди | уреди извор]

GABRR3+protein,+human на US National Library of Medicine Medical Subject Headings (MeSH)

[refGRCm38Ensembl-1] а ^б ^в GRCm38: Ensembl release 89: ENSMUSG00000074991 - Ensembl, May 2017

[2] „Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] „Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10542332-4] Bailey ME, Albrecht BE, Johnson KJ, Darlison MG (1999). „Genetic linkage and radiation hybrid mapping of the three human GABA(C) receptor rho subunit genes: GABRR1, GABRR2 and GABRR3”. Biochim. Biophys. Acta. 1447 (2–3): 307—12. PMID 10542332. doi:10.1016/S0167-4781(99)00167-0.

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