Inozitol-heksakisfosfat kinaza
| Inozitol-heksakisfosfat kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.4.21 | ||||||||
| CAS broj | 176898-37-6 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Inozitol-heksakisfosfat kinaza (EC 2.7.4.21, ATP:1D-mio-inozitol-heksakisfosfat fosfotransferaza) je enzim sa sistematskim imenom ATP:1D-mio-inozitol-heksakisfosfat 5-fosfotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (2) ATP + 1D-mio-inozitol 1,3,4,5,6-pentakisfosfat ADP + 1D-mio-inozitol difosfat tetrakisfosfat (izomerska konfiguracija je nepoznata)
Kod sisara su poznate tri izoforme.
Reference[уреди | уреди извор]
- ^ Saiardi, A., Erdjument-Bromage, H., Snowman, A.M., Tempst, P. and Snyder, S.H. (1999). „Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases”. Curr. Biol. 9: 1323—1326. PMID 10574768.
- ^ Schell, M.J., Letcher, A.J., Brearley, C.A., Biber, J., Murer, H. and Irvine, R.F. (1999). „PiUS (Pi uptake stimulator) is an inositol hexakisphosphate kinase”. FEBS Lett. 461: 169—172. PMID 10567691.
- ^ Albert, C., Safrany, S.T., Bembenek, M.E., Reddy, K.M., Reddy, K.K., Falck, J.-R., Bröcker, M., Shears, S.B. and Mayr, G.W. (1997). „Biological variability in the structures of diphosphoinositol polyphosphates in Dictyostelium discoideum and mammalian cells”. Biochem. J. 327: 553—560. PMID 9359429.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Inositol-hexakisphosphate+kinase на US National Library of Medicine Medical Subject Headings (MeSH)
