Karboksipeptidaza M
| Karboksipeptidaza M | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.17.12 | ||||||||
| CAS broj | 120038-28-0 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Karboksipeptidaza M (EC 3.4.17.12, CPM) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Odvajanje C-terminalnih argininskih i lizinskih ostataka sa polipeptida
Ovaj membranski enzim je optimalno aktivan pri neutralnom pH.
Reference[уреди | уреди извор]
- ^ Skidgel, R.A. (1988). „Basic carboxypeptidases: Regulators of peptide hormone activity”. Trends Pharmacol. Sci. 9: 303—304. PMID 3074547.
- ^ Deddish, P.A., Skidgel, R.A. and Erdös, E.G. (1989). „Enhanced Co2+ activation and inhibitor binding of carboxypeptidase M at low pH”. Biochem. J. 261: 289—291. PMID 2775217.
- ^ Skidgel, R.A., Davis, R.M. and Tan, F. (1989). „Human carboxypeptidase M. Purification and characterization of membrane-bound carboxypeptidase that cleaves peptide hormones”. J. Biol. Chem. 264: 2236—2241. PMID 2914904.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- Carboxypeptidase+M на US National Library of Medicine Medical Subject Headings (MeSH)
