MK-212

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MK-212
MK-212.svg
Nazivi
IUPAC naziv
2-Hloro-6-(1-piperazinil)pirazin
Drugi nazivi
CPP
Identifikacija
3D model (Jmol)
ChemSpider
Svojstva
C8H11ClN4
Molarna masa 198,65 g·mol−1
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
Reference infokutije

MK-212 (CPP, 6-hloro-2-(l-piperazinil)pirazin)[3] je serotoninski agonist.[4] On promoviše sekreciju serumskog prolaktina i kortizola kod ljudi.[5]

Reference[уреди]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  edit
  2. Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Clineschidmt, BV (1979). „MK-212: A serotonin-like agonist in the CNS”. General pharmacology. 10 (4): 287—90. PMID 488663. 
  4. Bastani, B.; Nash, J. F.; Meltzer, H. Y. (1990). „Prolactin and Cortisol Responses to MK-212, a Serotonin Agonist, in Obsessive-Compulsive Disorder”. Archives of General Psychiatry. 47 (9): 833—9. PMID 2203327. doi:10.1001/archpsyc.1990.01810210041006. 
  5. Lowy, Martin T.; Meltzer, Herbert Y. (1988). „Stimulation of serum cortisol and prolactin secretion in humans by MK-212, a centrally active serotonin agonist”. Biological Psychiatry. 23 (8): 818—28. PMID 3365458. doi:10.1016/0006-3223(88)90070-4. 

Spoljašnje veze[уреди]