N-sulfoglukozaminska 3-sulfataza
(преусмерено са N-sulfoglukozamin-3-sulfataza)
| N-sulfoglukozaminska 3-sulfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.6.15 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
N-sulfoglukozaminska 3-sulfataza (EC 3.1.6.15, hondroitinsulfataza) je enzim sa sistematskim imenom N-sulfo-3-sulfoglukozamin 3-sulfohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hidroliza 3-sulfatnih grupa N-sulfo-D-glukozamin 3-O-sulfatnih jedinica heparina
Enzim iz Flavobacterium heparinum takođe hidrolizuje N-acetil-D-glukozamin 3-O-sulfat.
Reference[уреди | уреди извор]
- ^ Bruce, J.S., McLean, M.W., Long, W.F. and Williamson, F.B. (1985). „Flavobacterium heparinum 3-O-sulphatase for N-substituted glucosamine 3-O-sulphate”. Eur. J. Biochem. 148: 359—365. PMID 3987694.
- ^ Leder, I.G. (1980). „A novel 3-O sulfatase from human urine acting on methyl-2-deoxy-2-sulfamino-α-D-glucopyranoside 3-sulfate”. Biochem. Biophys. Res. Commun. 94: 1183—1189. PMID 7396957.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- N-sulfoglucosamine-3-sulfatase на US National Library of Medicine Medical Subject Headings (MeSH)
