O-acetilhomoserin aminokarboksipropiltransferaza
| O-acetilhomoserin aminokarboksipropiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.5.1.49 | ||||||||
| CAS broj | 37290-90-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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O-acetilhomoserin aminokarboksipropiltransferaza (EC 2.5.1.49, O-acetil-L-homoserin acetat-lijaza (dodaje metantiol), O-acetil-L-homoserin sulfhidrolaza, O-acetilhomoserin (tiol)-lijaza, O-acetilhomoserinsla sulfhidrolaza, metioninska sintaza) je enzim sa sistematskim imenom O-acetil-L-homoserin:metantiol 3-amino-3-karboksipropiltransferaza.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim takođe reaguje sa drugim tiolima i H2S, čime se formira homocistein ili tioetri.
Reference[уреди | уреди извор]
- ^ Kerr, D. (1971). „O-Acetylhomoserine sulfhydrylase (Neurospora)”. Methods Enzymol. 17B: 446—450.
- ^ Smith, I.K. & Thompson, J.F. (1969). „Utilization of S-methylcysteine and methylmercaptan by methionineless mutants of Neurospora and the pathway of their conversion to methionine. II. Enzyme studies”. Biochim. Biophys. Acta. 184: 130—138. PMID 5791104.
- ^ Yamagata, S. & Takeshima, K. (1976). „O-Acetylserine and O-acetylhomoserine sulfhydrylase of yeast. Further purification and characterization as a pyridoxal enzyme”. J. Biochem. (Tokyo). 80: 777—785. PMID 795806.
- ^ Yamagata, S. (1976). „O-Acetylserine and O-acetylhomoserine sulfhydrylase of yeast. Subunit structure”. J. Biochem. (Tokyo). 80: 787—797. PMID 795807.
- ^ Yamagata, S., Takeshima, K. and Naikai, N. (1974). „Evidence for the identity of O-acetylserine sulfhydrylase with O-acetylhomoserine sulfhydrylase in yeast”. J. Biochem. (Tokyo). 75: 1221—1229. PMID 4609980.
- ^ Yamagata, S. (1989). „Roles of O-acetyl-L-homoserine sulfhydrylases in micro-organisms”. Biochimie. 71: 1125—1143. PMID 2517474.
- ^ Shimizu, H., Yamagata, S., Masui, R., Inoue, Y., Shibata, T., Yokoyama, S., Kuramitsu, S. and Iwama, T. (2001). „Cloning and overexpression of the oah1 gene encoding O-acetyl-L-homoserine sulfhydrylase of Thermus thermophilus HB8 and characterization of the gene product”. Biochim. Biophys. Acta. 1549: 61—72. PMID 11566369.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- O-acetylhomoserine+aminocarboxypropyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
