Skimnol sulfotransferaza
| Skimnol sulfotransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.8.2.32 | ||||||||
| CAS broj | 220581-70-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Skimnol sulfotransferaza (EC 2.8.2.32, Scymnol sulfotransferase) je enzim sa sistematskim imenom 3'-fosfoadenozin 5'-fosfosulfat:5beta-skimnol sulfotransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 3'-fosfoadenozin 5'-fosfosulfat + 5beta-skimnol adenozin 3',5'-bisfosfat + 5beta-skimnol sulfat
Enzim iz ajkule Heterodontus portusjacksoni može da sulfatira C27 žučnih soli 5beta-skimnol (prirodna žučna so) i 5alfa-ciprinol (žučna so šarana).
Reference[уреди | уреди извор]
- ^ Macrides, T.A., Faktor, D.A., Kalafatis, N. and Amiet, R.G. (1994). „Enzymic sulfation of bile salts. Partial purification and characterization of an enzyme from the liver of the shark Heterodontus portusjacksoni that catalyses the sulfation of the shark bile steroid 5β-scymnol”. Comp. Biochem. Physiol. 107: 461—469. PMID 7749614.
- ^ Pettigrew, N.E., Wright, P.F.A. and Macrides, T.A. (1998). „Investigation of 5β-scymnol sulfotransferase from the kidney and testes of Heterodontus portusjacksoni”. Comp. Biochem. Physiol. 121: 243—249.
- ^ Pettigrew, N.E., Wright, P.F.A. and Macrides, T.A. (1998). „5β-Scymnol sulfotransferase isolated from the tissues of an Australian shark species”. Comp. Biochem. Physiol. 121: 299—307.
- ^ Pettigrew, N.E., Wright, P.F.A. and Macrides, T.A. (1998). „5β-scymnol sulfotransferase isolated from the liver of two Australian ray species”. Comp. Biochem. Physiol. 121: 341—348.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Scymnol+sulfotransferase на US National Library of Medicine Medical Subject Headings (MeSH)
