Tripsin

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Tripsin
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Identifikatori
EC broj 3.4.21.4
CAS broj 2594141
Baze podataka
IntEnz IntEnz pregled
BRENDA BRENDA pristup
ExPASy NiceZyme pregled
KEGG KEGG pristup
MetaCyc metabolički put
PRIAM profil
Strukture PBP RCSB PDB PDBe PDBsum

Tripsin (EC 3.4.21.4, alfa-tripsin, beta-tripsin, kokunaza, parenzim, parenzimol, triptar, tripur, pseudotripsin, tripcelim, sperm receptorska hidrolaza) je enzim.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju

Preferentno odvajanje: Arg-, Lys-

Jednolančani polipeptid goveđeg beta-tripsina se formira iz tripsinogena razlaganjem jedne peptidne veze.

Reference[уреди]

  1. Huber, R. & Bode, W. (1978). „Structural basis of the activation and action of trypsin”. Acc. Chem. Res. 11: 114—122. 
  2. Walsh, K.A. (1970). „Trypsinogens and trypsins of various species”. Methods Enzymol. 19: 41—63. 
  3. Read, R.J., Brayer, G.D., Jurásek, L. and James, M.N.G. (1984). „Critical evaluation of comparative model building of Streptomyces griseus trypsin”. Biochemistry. 23: 6570—6575. PMID 6442164. 
  4. Fiedler, F. (1987). „Effects of secondary interactions on the kinetics of peptide and peptide ester hydrolysis by tissue kallikrein and trypsin”. Eur. J. Biochem. 163: 303—312. PMID 3643848. 
  5. Fletcher, T.S., Alhadeff, M., Craik, C.S. and Largman, C. (1987). „Isolation and characterization of a cDNA encoding rat cationic trypsinogen”. Biochemistry. 26: 3081—3086. PMID 3112218. 
  6. Polgár, L. (1987). „Structure and function of serine proteases”. Ур.: Neuberger, A. and Brocklehurst, K. New Comprehensive Biochemistry: Hydrolytic Enzymes. 16. Amsterdam: Elsevier. стр. 159—200. 
  7. Tani, T., Kawashima, I., Mita, K. and Takiguchi, Y. (1990). „Nucleotide sequence of the human pancreatic trypsinogen III cDNA”. Nucleic Acids Res. 18: 1631—1631. PMID 2326201. 

Литература[уреди]

  • Polgár, L. (1987). „Structure and function of serine proteases”. Ур.: Neuberger, A. and Brocklehurst, K. New Comprehensive Biochemistry: Hydrolytic Enzymes. 16. Amsterdam: Elsevier. стр. 159—200. 

Spoljašnje veze[уреди]