Undekaprenil-fosfat 4-dezoksi-4-formamido-L-arabinoza transferaza
| Undekaprenil-fosfat 4-dezoksi-4-formamido-L-arabinoza transferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.8.30 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Undekaprenil-fosfat 4-dezoksi-4-formamido-L-arabinoza transferaza (EC 2.7.8.30, undekaprenil-fosfat Ara4FN transferaza, Ara4FN transferaza, protein polimiksinske otpornosti PmrF, UDP-4-amino-4-dezoksi-alfa-L-arabinoza:ditrans,policis-undekaprenil fosfat 4-amino-4-dezoksi-alfa-L-arabinoziltransferaza) je enzim sa sistematskim imenom UDP-4-amino-4-dezoksi-alfa-L-arabinoza:ditrans,oktacis-undekaprenil fosfat 4-amino-4-dezoksi-alfa-L-arabinosiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-4-dezoksi-4-formamido-beta-L-arabinopiranoza + ditrans,oktacis-undekaprenil fosfat UDP + 4-dezoksi-4-formamido-alfa-L-arabinopiranozil ditrans,oktacis-undekaprenil fosfat
Ovaj enzim nije aktivan sa UDP-4-amino-4-dezoksi-beta-L-arabinozom.
Reference[уреди | уреди извор]
- ^ Breazeale, S.D., Ribeiro, A.A. and Raetz, C.R. (2002). „Oxidative decarboxylation of UDP-glucuronic acid in extracts of polymyxin-resistant Escherichia coli. Origin of lipid a species modified with 4-amino-4-deoxy-L-arabinose”. J. Biol. Chem. 277: 2886—2896. PMID 11706007.
- ^ Breazeale, S.D., Ribeiro, A.A., McClerren, A.L. and Raetz, C.R.H. (2005). „A formyltransferase required for polymyxin resistance in Escherichia coli and the modification of lipid A with 4-amino-4-deoxy-L-arabinose. Identification and function of UDP-4-deoxy-4-formamido-L-arabinose”. J. Biol. Chem. 280: 14154—14167. PMID 15695810.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- Undecaprenyl-phosphate+4-deoxy-4-formamido-L-arabinose+transferase на US National Library of Medicine Medical Subject Headings (MeSH)
