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(1) Osnovni domeni |
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| (1.1) Osnovni leucinski zatvarač (bZIP) | Aktivirajući transkripcioni faktor ( AATF, 1, 2, 3, 4, 5, 6, 7) • AP-1 ( c-Fos, FOSB, FOSL1, FOSL2, c-Jun, JUNB, JUND) • BACH ( 1, 2) • BATF • BLZF1 • C/EBP ( α, β, γ, δ, ε, ζ) • CREB ( 1, 3, L1) • CREM • DBP • DDIT3 • GABPA • HLF • MAF ( B, F, G, K) • NFE ( 2, L1, L2) • NFIL3 • NRL • NRF1 • XBP1 |
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| (1.2) Osnovni heliks-petlja-heliks (bHLH) | ATOH1 • AhR • AHRR • ARNT • ASCL1 • BHLHB2 • BMAL ( ARNTL, ARNTL2) • CLOCK • EPAS1 • HAND ( 1, 2) • HES ( 5, 6) • HEY ( 1, 2, L) • HES1 • HIF ( 1A, 3A) • ID ( 1, 2, 3, 4) • LYL1 • MXD4 • MYCL1 • MYCN • Myogenic regulatorni faktori ( MyoD, Myogenin, MYF5, MYF6) • Neurogenini ( 1, 2, 3) • NeuroD ( 1, 2) • NPAS ( 1, 2, 3) • OLIG ( 1, 2) • Pho4 • Scleraxis • TAL ( 1, 2) • Twist • USF1 |
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| (1.3) bHLH-ZIP | |
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| (1.4) NF-1 | |
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| (1.5) RF-X | |
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| (1.6) Osnovni heliks-razmak-heliks (bHSH) | |
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| (2.1) Nuklearni receptor (Cys4) | potfamilija 1 ( Tiroidni hormon ( α, β), CAR, FXR, LXR ( α, β), PPAR ( α, β/δ, γ), PXR, RAR ( α, β, γ), ROR ( α, β, γ), Rev-ErbA ( α, β), VDR) potfamilija 2 ( COUP-TF ( I, II), Ear-2, HNF4 ( α, γ), PNR, RXR ( α, β, γ), Testikularni receptor ( 2, 4), TLX) potfamilija 3 ( Steroidni hormon ( Androgen, Estrogen ( α, β), Glukokortikoid, Mineralokortikoid, Progesteron), Estrogen-vezani ( α, β, γ)) potfamilija 4 NUR ( NGFIB, NOR1, NURR1) • potfamilija 5 ( LRH-1, SF1) • potfamilija 6 ( GCNF) • potfamilija 0 ( DAX1, SHP) |
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| (2.2) Drugi Cys4 | |
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| (2.3) Cys2His2 | Generalni transkripcioni faktori ( TFIIA, TFIIB, TFIID, TFIIE, TFIIF ( 1, 2), TFIIH ( 1, 2, 4, 2I, 3A, 3C1, 3C2)) ATBF1 • BCL ( 6, 11A, 11B) • CTCF • E4F1 • EGR ( 2, 3) • ERV3 • GFI1 • GLI-Kruppel familija ( 1, 2, 3, REST, S2, YY1) • HIC ( 1, 2) • HIVEP ( 1, 2, 3) • IKZF ( 1, 2, 3) • ILF ( 2, 3) • KLF ( 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 17) • MTF1 • MYT1 • OSR1 • SP ( 1, 2, 4, 7) • WT1 • Zbtb7 ( 7A, 7B) • ZBTB ( 16, 17, 20, 32, 33, 40) • cink prst ( 3, 7, 9, 10, 19, 22, 24, 33B, 34, 35, 41, 43, 44, 51, 74, 143, 146, 148, 165, 202, 217, 219, 238, 239, 259, 267, 268, 281, 295, 318, 330, 346, 350, 365, 366, 384, 423, 451, 452, 471, 593, 638, 649, 655) |
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| (2.4) Cys6 | |
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| (2.5) Naizmenična kompozicija | |
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| (3.1) Homeodomen | ARX • CDX ( 1, 2) • CRX • CUTL1 • DBX ( 1, 2) • DLX ( 3, 4, 5) • EMX2 • EN ( 1, 2) • FHL ( 1, 2, 3) • HESX1 • HHEX • HLX • Homeobox ( A1, A2, A3, A4, A5, A7, A9, A10, A11, A13, B1, B2, B3, B4, B5, B6, B7, B8, B9, B13, C4, C5, C6, C8, C9, C10, C11, C13, D1, D3, D4, D8, D9, D10, D11, D12, D13) • HOPX • IRX ( 1, 2, 3, 4, 5, 6, MKX) • LMX ( 1A, 1B) • MEIS ( 1, 2) • MEOX2 • MNX1 • MSX ( 1, 2) • NANOG • NKX ( 2-1, 2-2, 2-3, 2-5, 3-1, 3-2, 6-1, 6-2) • PBX ( 1, 2, 3) • PHF ( 1, 3, 6, 8, 10, 16, 17, 20, 21A) • PITX ( 1, 2, 3) • POU domen ( PIT-1, BRN-3: A, B, C, Oktamer transkripcioni faktor: 1, 2, 3/4, 6, 7, 11) • OTX ( 1, 2) • PDX1 • ZEB ( 1, 2) |
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| (3.2) Paired box | |
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| (3.3) Fork glava / winged heliks | E2F ( 1, 2, 3, 4, 5) • FOX proteini ( C1, C2, D3, E1, G1, H1, K2, L2, M1, N3, O1, O3, O4, P1, P2, P3) |
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| (3.4) Faktori toplotnog šoka | |
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| (3.5) Triptofan klasteri | ELF ( 2, 4, 5) • EGF • ELK ( 1, 3, 4) • ERF • ERG • ETS ( 1, 2, SPIB) • ETV ( 1, 4, 5, 6) • FLI1 • Interferon regulatorni faktori ( 1, 2, 3, 4, 5, 6, 7, 8) • MYB • MYBL2 |
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| (3.6) TEA domen | transkripcioni pojačivač faktor ( 1, 2, 3, 4) |
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(4) β-Scaffold faktori sa manjim žljebnim kontaktima |
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| (4.1) Rel homologni region | |
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| (4.2) STAT | |
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| (4.3) p53 | |
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| (4.4) MADS kutija | |
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| (4.6) TATA vezujući proteini | |
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| (4.7) Grupa visoke pokretljivosti | HMGB ( 1, 2, 3) • HNF ( 1A, 1B) • LEF1 • SOX ( 1, 2, 3, 4, 5, 6, 8, 9, 10, 11, 12, 13, 14, 15, 18, 21) • SRY • SSRP1 • TCF ( 3, 4) • TOX ( 1, 2, 3, 4) |
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| (4.10) Domen hladnog šoka | |
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| (4.11) Runt | |
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(0) Drugi transkripcioni faktori |
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| (0.2) HMGI(Y) | |
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| (0.3) Džep domen | |
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| (0.5) AP-2/EREBP-vezani faktori | |
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| (0.6) Razno | ARID (1A, 1B, 2, 3A, 3B, 4A) • CAP • IFI (16, 35) • MLL (2, 3, T1) • MNDA • NFY (A, B, C) • Ro/Sigma |
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vidi isto transkripcioni faktor/koregulator nedostataka
B bsyn: dnk ( repl, cycl, reco, repr) · tscr ( fact, tcrg, nucl, rnat, rept, ptts) · tltn ( risu, pttl, nexn) · dnab, rnab/ runp · stru ( domn, 1°, 2°, 3°, 4°) |
