2,6-dihidroksipiridin 3-monooksigenaza
| 2,6-Dihidroksipiridin 3-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.10 | ||||||||
| CAS broj | 39279-38-4 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
2,6-Dihidroksipiridin 3-monooksigenaza (EC 1.14.13.10, 2,6-dihidroksipiridinska oksidaza) je enzim sa sistematskim imenom 2,6-dihidroksipiridin,NADH:kiseonik oksidoreduktaza (3-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 2,6-dihidroksipiridin + NADH + H+ + O2 2,3,6-trihidroksipiridin + NAD+ + H2O
Ovaj enzim je flavoprotein.
Reference[уреди | уреди извор]
- ^ Holmes, P.E. & Rittenberg, S.C. (1972). „The bacterial oxidation of nicotine. VII. Partial purification and properties of 2,6-dihydroxypyridine oxidase”. J. Biol. Chem. 247: 7622—7627. PMID 4344227.
- ^ Holmes, P.E., Rittenberg, S.C. and Knackmuss, H.J. (1972). „The bacterial oxidation of nicotine. 8. Synthesis of 2,3,6-trihydroxypyridine and accumulation and partial characterization of the product of 2,6-dihydroxypyridine oxidation”. J. Biol. Chem. 247: 7628—7633. PMID 4636328.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze[уреди | уреди извор]
- 2,6-dihydroxypyridine+3-monooxygenase на US National Library of Medicine Medical Subject Headings (MeSH)
