2-Fosfo-L-laktat transferaza
| 2-Fosfo-L-laktat transferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.8.28 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
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2-Fosfo-L-laktat transferaza (EC 2.7.8.28, LPPG:Fo 2-fosfo-L-laktat transferaza, LPPG:7,8-didemetil-8-hidroksi-5-deazariboflavin 2-fosfo-L-laktat transferaza, MJ1256, laktil-2-difosfo-(5')guanozin:Fo 2-fosfo-L-laktat transferaza, CofD) je enzim sa sistematskim imenom (2S)-laktil-2-difosfo-5'-guanozin:7,8-didemetil-8-hidroksi-5-deazariboflavin 2-fosfo-L-laktat transferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (2S)-laktil-2-difosfo-5'-guanozin + 7,8-didemetil-8-hidroksi-5-deazariboflavin GMP + koenzim F420-0
Ovaj enzim učestvuje u biosintezi koenzima F420.
Reference[уреди | уреди извор]
- ^ Graupner, M., Xu, H. and White, R.H. (2002). „Characterization of the 2-phospho-L-lactate transferase enzyme involved in coenzyme F420 biosynthesis in Methanococcus jannaschii”. Biochemistry. 41: 3754—3761. PMID 11888293.
- ^ Forouhar, F., Abashidze, M., Xu, H., Grochowski, L.L., Seetharaman, J., Hussain, M., Kuzin, A., Chen, Y., Zhou, W., Xiao, R., Acton, T.B., Montelione, G.T., Galinier, A., White, R.H. and Tong, L. (2008). „Molecular insights into the biosynthesis of the F420 coenzyme”. J. Biol. Chem. 283: 11832—11840. PMID 18252724.
Literatura[уреди | уреди извор]
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze[уреди | уреди извор]
- 2-phospho-L-lactate+transferase на US National Library of Medicine Medical Subject Headings (MeSH)
